| Regional diastolic contour abnormalities during contrast stress echocardiography: improved detection of coronary artery disease. | |
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MedLine Citation:
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PMID: 18926388 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Use of contrast improves detection of systolic regional wall motion abnormalities (RWMAs) during stress echocardiography. We evaluated regional diastolic contour abnormalities (RDCAs) that were associated with coronary artery disease (CAD). METHODS: From August of 2003 to September of 2004, we evaluated 89 patients who underwent contrast stress echocardiography (CSE) and coronary angiography within a 3-month period ("invasive" group) and 17 patients with lower CAD risk who underwent CSE only ("reference" group). RESULTS: RDCAs were present in 73 patients in the invasive group and were associated with higher Framingham risk scores (relative risk, 3.6; 95% confidence interval, 1.9-6.6). RDCAs were present in 1 patient in the reference group. When combined with RWMA, RDCA improved sensitivity of CSE from 78% to 97% and specificity from 26% to 59% (diagnostic threshold for CAD was 70% stenosis). CONCLUSION: RDCAs were a novel observation associated with higher CAD risk and improved the diagnostic accuracy of CSE. |
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Authors:
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Sonja Cukon-Buttignoni; Sahar S Abdelmoneim; Jo-Ellen Ehrsam; Marion E Barnes; Mary E Hagen; Lori A Carlson; Sabino Iliceto; Sharon L Mulvagh |
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Publication Detail:
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Type: Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography Volume: 21 ISSN: 1097-6795 ISO Abbreviation: J Am Soc Echocardiogr Publication Date: 2008 Oct |
Date Detail:
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Created Date: 2008-10-17 Completed Date: 2009-01-09 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8801388 Medline TA: J Am Soc Echocardiogr Country: United States |
Other Details:
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Languages: eng Pagination: 1109-15 Citation Subset: IM |
Affiliation:
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Division of Cardiovascular Diseases, Rochester, Minnesota, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Contrast Media Coronary Artery Disease / complications, ultrasonography* Echocardiography / methods* Exercise Test* Female Fluorocarbons / diagnostic use* Humans Image Enhancement / methods* Male Middle Aged Reproducibility of Results Sensitivity and Specificity Ventricular Dysfunction, Left / etiology, ultrasonography* |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media; 0/Definity; 0/Fluorocarbons |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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