| Regional corpus callosum morphometry: effect of field strength and pulse sequence. | |
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MedLine Citation:
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PMID: 19856453 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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PURPOSE: To investigate whether scanning at different field strengths and pulse sequences would influence reproducibility of corpus callosum (CC) morphometric measurements as variations in scanning parameters may result in differences in contrast properties between resulting images that are independent of the underlying tissue but rather reflect the physics of the imaging process. MATERIALS AND METHODS: Ten subjects were scanned twice at 3T using magnetization-prepared rapid gradient-echo imaging (MPRAGE) and modified driven equilibrium Fourier transform (MDEFT) sequences and once at 1.5T using MPRAGE. Cross-sectional area measurements of four callosal regions were performed on midsagittal magnetic resonance imaging (MRI) sections. RESULTS: Repeated measures analysis of variance with four regions as dependent variables and three scanning protocols (1.5T MPRAGE, 3T MPRAGE and 3T MDEFT) as independent variables revealed no significant region by protocol interaction: F(6,54) = 0.69, P = 0.52. Reliability measures for (3T MPRAGE/3T MDEFT) and (1.5T MPRAGE/3T MPRAGE; 1.5T MPRAGE/3T MDEFT) comparisons were high, ranging between 0.90 and 0.97. CONCLUSION: Based on our results, combining and comparing CC morphometric data obtained at different field strengths and/or with different pulse sequences appears possible. |
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Authors:
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Ihssan A Abdul-Kareem; Andrej Stancak; Laura M Parkes; Vanessa Sluming |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Journal of magnetic resonance imaging : JMRI Volume: 30 ISSN: 1522-2586 ISO Abbreviation: J Magn Reson Imaging Publication Date: 2009 Nov |
Date Detail:
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Created Date: 2009-10-29 Completed Date: 2010-01-21 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 9105850 Medline TA: J Magn Reson Imaging Country: United States |
Other Details:
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Languages: eng Pagination: 1184-90 Citation Subset: IM |
Affiliation:
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Magnetic Resonance and Image Analysis Research Centre, School of Health Sciences, University of Liverpool, Liverpool, UK. Ihssan.abdulkareem@liv.ac.uk |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Adult Algorithms Brain Mapping / methods Contrast Media / pharmacology Corpus Callosum / pathology* Female Fourier Analysis Humans Image Processing, Computer-Assisted / methods Magnetic Resonance Imaging / methods* Male Phantoms, Imaging Reproducibility of Results Software |
| Chemical | |
Reg. No./Substance:
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0/Contrast Media |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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