| Regional circulatory responses to hindlimb work in developing swine. | |
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MedLine Citation:
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PMID: 2271716 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Circulatory effects of hindlimb work were studied in 29 swine (aged 1 day to 1 month) anesthetized with pentobarbital. Femoral, renal and intestinal blood flow, resistance and autoregulatory capability were determined at different levels of hindlimb oxygen consumption before and during distal sciatic nerve stimulation. Increases in oxygen consumption were accompanied by hyperemia at all ages, but by increased oxygen extraction only in 2-week and 1-month-old animals, without evidence of autoregulation. Blood flow was consistently redistributed from the kidney and small intestine only in neonates. Older animals generally sustained autoregulation of renal and intestinal blood flows throughout experiments. We concluded that hindlimb work evokes age-related adjustments in regional blood flow that reflect the balance of neural and autoregulatory control. |
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Authors:
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N M Buckley; I D Frasier |
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Publication Detail:
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Type: Journal Article; Research Support, U.S. Gov't, P.H.S. |
Journal Detail:
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Title: Biology of the neonate Volume: 58 ISSN: 0006-3126 ISO Abbreviation: Biol. Neonate Publication Date: 1990 |
Date Detail:
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Created Date: 1991-02-25 Completed Date: 1991-02-25 Revised Date: 2007-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0247551 Medline TA: Biol Neonate Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 208-19 Citation Subset: IM |
Affiliation:
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Department of Physiology and Biophysics, Albert Einstein College of Medicine, Bronx, N.Y. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Blood Gas Analysis Blood Pressure Hindlimb / blood supply* Homeostasis Hyperemia / physiopathology Intestines / blood supply* Oxygen Consumption / physiology* Regional Blood Flow Renal Circulation* Sciatic Nerve / physiology Swine / growth & development* Vascular Resistance Venous Pressure |
| Grant Support | |
ID/Acronym/Agency:
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HL-21865/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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