Document Detail

Regional cerebral glucose metabolism of newborn infants measured by positron emission tomography.
MedLine Citation:
PMID:  6602073     Owner:  NLM     Status:  MEDLINE    
The new diagnostic technique, positron emission tomography with 18F-2-fluoro-2-deoxy-D-glucose (18FDG), was used to measure regional cerebral glucose metabolism in five newborn infants with demonstrated structural abnormalities of the brain. 18FDG was synthesized, diluted in normal saline and injected intravenously. After one hour, tomographic slices of the brain were obtained, the level of the slices being defined relative to the cerebral ventricles. Glucose metabolism of grey- and white-matter structures in the brain could be differentiated clearly. Decreased glucose metabolism was identified in regions of the brain shown by computerized axial tomography to be structurally abnormal. Positron emission tomography is a promising new diagnostic tool for the study of newborn infants with suspected abnormalities of brain function.
L W Doyle; C Nahmias; G Firnau; D B Kenyon; E S Garnett; J C Sinclair
Related Documents :
19756463 - Seeing it coming: infants' brain responses to looming danger.
3324793 - Neuroradiological aspects of infantile spasms.
10452213 - Proximodistal structure of early reaching in human infants.
Publication Detail:
Type:  Comparative Study; Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Developmental medicine and child neurology     Volume:  25     ISSN:  0012-1622     ISO Abbreviation:  Dev Med Child Neurol     Publication Date:  1983 Apr 
Date Detail:
Created Date:  1983-07-08     Completed Date:  1983-07-08     Revised Date:  2009-11-11    
Medline Journal Info:
Nlm Unique ID:  0006761     Medline TA:  Dev Med Child Neurol     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  143-51     Citation Subset:  IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Brain / metabolism*,  radiography,  radionuclide imaging
Glucose / metabolism*
Infant, Newborn
Tissue Distribution
Tomography, Emission-Computed*
Tomography, X-Ray Computed
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Decrease in the serum level of the C3 complement component in noninsulin dependent diabetes of recen...
Next Document:  Outcome of high-risk neonates with ventriculomegaly.