| Regional cerebral blood flow response to hypocapnia in the contralateral hemisphere of patients with acute cerebral infarction. | |
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MedLine Citation:
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PMID: 1179457 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The rCBF response to hypocapnia induced by active short-term hyperventilation was determined in the contralateral hemispheres of ten patients with acute unilateral cerebral infarction. Overall rCBF reduction occurred in only two patients. Regional or widespread abnormal responses to Paco2 reduction manifested as either no change or a paradoxical increase in the rCBF were observed in eight patients. The hemispheric mean rCBF reduction following hypocapnia was diminished as compared with control subjects. Our findings suggest that an impairment of the chemical control of rCBF may occur in the non-infarcted hemisphere during the early period following the onset of cerebral infarction. The pathophysiological mechanisms which may underlie this abnormal rCBF reactivity to Paco2 reduction are considered. |
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Authors:
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E Melamed; S Lavy; Z Portnoy |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Stroke; a journal of cerebral circulation Volume: 6 ISSN: 0039-2499 ISO Abbreviation: Stroke Publication Date: 1975 Sep-Oct |
Date Detail:
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Created Date: 1975-12-28 Completed Date: 1975-12-28 Revised Date: 2004-11-17 |
Medline Journal Info:
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Nlm Unique ID: 0235266 Medline TA: Stroke Country: UNITED STATES |
Other Details:
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Languages: eng Pagination: 503-8 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Disease Adult Aged Brain / blood supply* Carbon Dioxide Cerebrovascular Circulation Female Humans Infarction / physiopathology* Male Middle Aged |
| Chemical | |
Reg. No./Substance:
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124-38-9/Carbon Dioxide |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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