| Regional cerebral blood flow in the persistent vegetative state. | |
| | |
MedLine Citation:
|
PMID: 2477738 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Regional cerebral blood flow (CBF) in eight patients in a persistent vegetative state was measured and compared with that in five healthy volunteers. The patients were classified into three groups: Group 1 (locked-in syndrome) consisted of a single patient, Group 2 (typical vegetative state) of five patients, and Group 3 (prolonged coma) of two patients. CBF was measured early after onset by single photon emission computed tomography with 123I-N-isopropyl-p-iodo-amphetamine and/or 99mTc-hexamethyl-propyleneamine oxime. The regions of interest (ROIs) were the bilateral frontal, temporal, parietal, occipital, and cerebellar areas and basal ganglia. The values obtained in these areas were averaged, and the ratio for each ROI [(the value in the ROI/the mean value) x 100] was calculated. "Hyperfrontal distribution" of CBF was found to be rare in both the normal condition and the vegetative state. Higher CBF values were noted in the left than in the right frontal area in four of the five volunteers but in only four of the eight patients. CBF distribution in the frontal lobe was characteristic for each group: Group 1 showed high CBF bilaterally, although the elevation was statistically significant only on the right side, and Group 3 exhibited significantly low values. In Group 2, CBF was variable but, for the most part, within normal limits. Awareness was closely correlated with frontal lobe function and alteration of CBF in the frontal region. |
| | |
Authors:
|
M Sato; R Kuroda; M Ioku; A Kim; S Tanaka; K Nakakita; A Kohama; C Fujii; S Ono; M Fukunaga |
Related Documents
:
|
17621818 - Endoscopic management of sinus disease with frontal lobe displacement. 7588588 - The pathophysiologic relationships between lesion pathology, intracranial ictal eeg ons... 16239178 - Single pulse electrical stimulation for identification of structural abnormalities and ... 7608298 - Neuropsychological and neuroanatomical correlates of confabulation. 17524198 - Discontinuation of non-nucleoside reverse transcriptase inhibitor-based highly active a... 618988 - A noninvasive method for the evaluation of tissue iron deposition in beta-thalassemia m... |
Publication Detail:
|
Type: Journal Article |
Journal Detail:
|
Title: Neurologia medico-chirurgica Volume: 29 ISSN: 0470-8105 ISO Abbreviation: Neurol. Med. Chir. (Tokyo) Publication Date: 1989 May |
Date Detail:
|
Created Date: 1989-11-20 Completed Date: 1989-11-20 Revised Date: 2004-11-17 |
Medline Journal Info:
|
Nlm Unique ID: 0400775 Medline TA: Neurol Med Chir (Tokyo) Country: JAPAN |
Other Details:
|
Languages: eng Pagination: 389-94 Citation Subset: IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Aged Cerebrovascular Circulation* Coma / physiopathology* Female Humans Male Middle Aged Tomography, Emission-Computed, Single-Photon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Regional cerebral blood flow and oxygen metabolism in normal pressure hydrocephalus after subarachno...
Next Document: Intracranial arteriovenous malformation: relationships between clinical and radiographic factors and...