| Regional blood flow and the localisation of lymphoblasts in the small intestine of the mouse: effect of an elemental diet. | |
| | |
MedLine Citation:
|
PMID: 6972889 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
To test the hypothesis that food antigens influence the in vivo migration of lymphoblasts to the small intestine, the effect of an elemental diet (Vivonex) on the distribution of lymphoblasts within the small intestine of mice has been examined. Viable lymphoblasts from the mesenteric nodes of conventionally fed animals were labelled in vitro and given intravenously to recipient mice fed either a standard diet or elemental diet. The localisation of these cells within the small intestine was altered in the animals fed the elemental diet but only in the distal half of the small intestine. The relationship of the localisation of blast cells to the delivery of cardiac output along the small intestine was examined by assessing cell localisation in conjunction with the distribution of an isotopic indicator (86RbC1). The results show that the pattern of localisation of lymphoblasts within the small intestine is related to the probability that they will be delivered to different regions by the blood stream. Therefore, the alterations in blast localisation in the small intestine of animals of the elemental diet can be viewed as a consequence of changes in the perfusion of the distal small intestine. These results do not support the concept that antigens directly influence the efficiency with which blast cells migrate into the intestinal mucosa. |
| | |
Authors:
|
C A Ottaway; D M Parrott |
Related Documents
:
|
18270839 - Dietary lipids alter the effect of steroids on the transport of fructose following inte... 10421389 - Whole-protein-based enteral formula stimulates intestinal ornithine decarboxylase activ... 20620329 - Dietary bile acid supplementation improves intestinal integrity and survival in a murin... 3653629 - Tissue-specific gene expression results from a purine- and pyrimidine-free diet and 6-m... 18373109 - Npc1l1 and sr-bi are involved in intestinal cholesterol absorption from small-size lipi... 15590889 - Involvement of mrp2 in hepatic and intestinal disposition of dinitrophenyl-s-glutathion... 2365939 - Lack of effect of vitamin b-6 supplementation on the lipoprotein profile of post-menopa... 2739509 - Effects of zinc and cholesterol/choleate on serum lipoproteins and the liver in rats. 12749939 - Effect on ejaculatory performance and semen parameters of sexually-satiated male goats ... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
|
Title: Gut Volume: 22 ISSN: 0017-5749 ISO Abbreviation: Gut Publication Date: 1981 May |
Date Detail:
|
Created Date: 1981-09-22 Completed Date: 1981-09-22 Revised Date: 2009-11-18 |
Medline Journal Info:
|
Nlm Unique ID: 2985108R Medline TA: Gut Country: ENGLAND |
Other Details:
|
Languages: eng Pagination: 376-82 Citation Subset: AIM; IM |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Cardiac Output Cell Movement Food, Formulated* Intestine, Small / blood supply*, cytology Lymphocytes / physiology* Mesentery Mice Mice, Inbred Strains Regional Blood Flow T-Lymphocytes / physiology |
| Comments/Corrections | |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Microcirculation of intestinal lymphoid follicles in rat Peyer's patches.
Next Document: Animal experiments on cementing small osteochondral fragments with fibrin glue