Document Detail


Regenerative medicine in dermatology: biomaterials, tissue engineering, stem cells, gene transfer and beyond.
MedLine Citation:
PMID:  20545761     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The term 'regenerative medicine' refers to a new and expanding field in biomedical research that focuses on the development of innovative therapies allowing the body to replace, restore and regenerate damaged or diseased cells, tissues and organs. It combines several technological approaches including the use of soluble molecules, biomaterials, tissue engineering, gene therapy, stem cell transplantation and the reprogramming of cell and tissue types. Because of its easy accessibility, skin is becoming an attractive model organ for regenerative medicine. Here, we review recent developments in regenerative medicine and their potential relevance for dermatology with a particular emphasis on biomaterials, tissue engineering, skin substitutes and stem cell-based therapies for skin reconstitution in patients suffering from chronic wounds and extensive burns.
Authors:
Christina Dieckmann; Regina Renner; Linda Milkova; Jan C Simon
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Experimental dermatology     Volume:  19     ISSN:  1600-0625     ISO Abbreviation:  Exp. Dermatol.     Publication Date:  2010 Aug 
Date Detail:
Created Date:  2010-07-26     Completed Date:  2011-01-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9301549     Medline TA:  Exp Dermatol     Country:  Denmark    
Other Details:
Languages:  eng     Pagination:  697-706     Citation Subset:  IM    
Affiliation:
Translational Centre for Regenerative Medicine, Leipzig University, Leipzig, Germany.
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MeSH Terms
Descriptor/Qualifier:
Biocompatible Materials
Dermatology / trends*
Gene Transfer Techniques / trends
Humans
Regenerative Medicine / trends*
Stem Cell Transplantation / trends
Tissue Engineering / trends
Chemical
Reg. No./Substance:
0/Biocompatible Materials

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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