Document Detail

Regenerative inductive therapy based on DDS technology of protein and gene.
MedLine Citation:
PMID:  17062395     Owner:  NLM     Status:  MEDLINE    
Recent development of biomedical engineering including biomaterials and drug delivery system (DDS) as well as basic biology and medicine has enabled cells to induce regeneration repairing of defective tissues as well as substitute the biological functions of damaged organs. For successful tissue regeneration, it is undoubtedly indispensable to give cells a local environment which allows cells to efficiently promote their proliferation and differentiation and consequently induce cell-based tissue regeneration. Tissue engineering is one of the biomedical forms to create this regeneration environment of cells. The tissue and organ repairing based on their regeneration induction has been realized by combining cells with the tissue engineering technology or methodology in a surgical or internally medical manner. This paper overviews the present status and future direction of tissue engineering for regenerative inductive therapy, briefly explaining the key technology of tissue engineering, especially DDS of growth factor and gene.
Yasuhiko Tabata
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Publication Detail:
Type:  Journal Article; Review    
Journal Detail:
Title:  Journal of drug targeting     Volume:  14     ISSN:  1061-186X     ISO Abbreviation:  J Drug Target     Publication Date:  2006  
Date Detail:
Created Date:  2006-10-25     Completed Date:  2007-02-05     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9312476     Medline TA:  J Drug Target     Country:  England    
Other Details:
Languages:  eng     Pagination:  483-95     Citation Subset:  IM    
Department of Biomaterials, Field of Tissue Engineering, Institute for Frontier Medical Sciences, Kyoto University, Sakyo-ku, Kyoto, 606-8507, Japan.
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MeSH Terms
Drug Delivery Systems / methods*
Growth Substances / administration & dosage*,  genetics,  physiology
Models, Biological
Regeneration / drug effects*,  physiology
Regenerative Medicine / methods*
Technology, Pharmaceutical / methods,  trends
Tissue Engineering / methods
Reg. No./Substance:
0/Growth Substances

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