Document Detail


Regenerative Therapies in Neonatology: Clinical Perspectives.
MedLine Citation:
PMID:  22718085     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Regenerative therapy based on stem cells is applied as standard therapy in pediatric oncology. Furthermore, they are frequently used to treat immunodeficiency disorders of infants. For severe neonatal diseases, e. g. hypoxic-ischemic encephalopathy in term neonates or bronchopulmonary dysplasia in preterm infants, animal models have been established. According to some first preclinical results stem cell administration appears as a promising tool to improve the clinical outcome in high-risk infants. Provided the benefit of regenerative therapies can further be evaluated in appropriate preclinical neonate models, carefully controlled clinical trials to assess the significance of regenerative therapies, such as autologous stem cell administration, are indicated.
Authors:
L Gortner; U Felderhoff-Müser; D Monz; K Bieback; H Klüter; R Jellema; B W Kramer; M Keller; I Reiss; P A Horn; B Giebel
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-6-20
Journal Detail:
Title:  Klinische Padiatrie     Volume:  -     ISSN:  1439-3824     ISO Abbreviation:  -     Publication Date:  2012 Jun 
Date Detail:
Created Date:  2012-6-21     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0326144     Medline TA:  Klin Padiatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© Georg Thieme Verlag KG Stuttgart · New York.
Affiliation:
Pediatric Hospital, University of the Saarland, Homburg, Germany.
Vernacular Title:
Regenerative Therapien in der Neonatologie: Perspektiven für die Klinik.
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