Document Detail


Refrigerator storage of expressed human milk in the neonatal intensive care unit.
MedLine Citation:
PMID:  19783003     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
OBJECTIVE: To provide recommendations for refrigerator storage of human milk, the overall integrity (bacterial growth, cell counts, and component concentrations) of milk was examined during 96 hours of storage at 4 degrees C. STUDY DESIGN: Fresh milk samples (n = 36) were divided and stored at 4 degrees C for 0, 24, 48, 72, and 96 hours. At each time, pH, white cell count, and osmolality were measured and additional samples were stored at -80 degrees C until analyzed for bacteria and concentrations of lactoferrin, secretory (s)IgA, fat, fatty acids, and protein. RESULTS: There were no significant changes for osmolality, total and Gram-negative bacterial colony counts or concentrations of sIgA, lactoferrin, and fat. Gram-positive colony counts (2.9 to 1.6 x 10(5) colony-forming units per mL), pH (7.21 to 6.68), white blood cell counts (2.31 to 1.85 x 10(6) cells per mL), and total protein (17.5 to 16.7 g/L) declined, and free fatty acid concentrations increased (0.35 to 1.28 g/L) as storage duration increased, P < .001. CONCLUSIONS: Changes were minimal and the overall integrity of milk during refrigerator storage was preserved. Fresh mother's milk may be stored at refrigerator temperature for as long as 96 hours.
Authors:
Meredith Slutzah; Champa N Codipilly; Debra Potak; Richard M Clark; Richard J Schanler
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Publication Detail:
Type:  Evaluation Studies; Journal Article    
Journal Detail:
Title:  The Journal of pediatrics     Volume:  156     ISSN:  1097-6833     ISO Abbreviation:  J. Pediatr.     Publication Date:  2010 Jan 
Date Detail:
Created Date:  2009-12-16     Completed Date:  2010-02-17     Revised Date:  2010-08-16    
Medline Journal Info:
Nlm Unique ID:  0375410     Medline TA:  J Pediatr     Country:  United States    
Other Details:
Languages:  eng     Pagination:  26-8     Citation Subset:  AIM; IM    
Affiliation:
Division of Neonatal-Perinatal Medicine, Schneider Children's Hospital, New Hyde Park, NY, USA.
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MeSH Terms
Descriptor/Qualifier:
Colony Count, Microbial
Fatty Acids, Nonesterified / analysis
Humans
Hydrogen-Ion Concentration
Intensive Care Units, Neonatal*
Milk, Human / chemistry
Osmolar Concentration
Refrigeration*
Time Factors
Chemical
Reg. No./Substance:
0/Fatty Acids, Nonesterified
Comments/Corrections
Comment In:
J Hum Lact. 2010 Aug;26(3):233-4   [PMID:  20689101 ]

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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