Document Detail


Refractory neuro-Behçet treated by tocilizumab: a case report.
MedLine Citation:
PMID:  23020826     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
A patient with central nervous system involvement of Behçet's disease was refractory to conventional immunosuppressive therapy and showed secondary failure of the anti-TNF agent infliximab. This presented as a progressive weakness of the legs and reduction in walking distance. The cerebrospinal fluid showed signs of inflammation including a vastly elevated IL-6 concentration. Given this result, the anti-IL-6 receptor antibody tocilizumab was administered and a good improvement of inflammatory parameters and a satisfactory increase of the walking distance were achieved.
Authors:
Piotr Urbaniak; Paul Hasler; Samuel Kretzschmar
Related Documents :
9776416 - Diffuse thin glomerular basement membrane in association with idiopathic membranous glo...
22402706 - Delayed preattentional functioning in early psychosis patients with cannabis use.
2221646 - Clinical course of anti-neutrophil cytoplasmic autoantibody-associated glomerulonephrit...
6878266 - Prednisone-induced increase of proteinuria in patients with a nephrotic syndrome.
22218446 - Tsh neurosecretory dysfunction (tsh-nd) in down syndrome (ds): low risk of progression ...
9696296 - Impaired sensorimotor gating in patients with non-epileptic seizures.
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-27
Journal Detail:
Title:  Clinical and experimental rheumatology     Volume:  -     ISSN:  0392-856X     ISO Abbreviation:  Clin. Exp. Rheumatol.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-10-1     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8308521     Medline TA:  Clin Exp Rheumatol     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Rheumaklinik und Institut für Physikalische Medizin und Rehabilitation, Kantonsspital Aarau AG, Aarau, Switzerland. piotr.urbaniak@ksa.ch.
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Descriptor/Qualifier:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


Previous Document:  Mitogen- and stress-activated kinases regulate progenitor cell proliferation and neuron development ...
Next Document:  Reader Reaction to "Using Regression Models to Analyze Randomized Trials: Asymptotically Valid Hypot...