| Refractory neuro-Behçet treated by tocilizumab: a case report. | |
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MedLine Citation:
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PMID: 23020826 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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A patient with central nervous system involvement of Behçet's disease was refractory to conventional immunosuppressive therapy and showed secondary failure of the anti-TNF agent infliximab. This presented as a progressive weakness of the legs and reduction in walking distance. The cerebrospinal fluid showed signs of inflammation including a vastly elevated IL-6 concentration. Given this result, the anti-IL-6 receptor antibody tocilizumab was administered and a good improvement of inflammatory parameters and a satisfactory increase of the walking distance were achieved. |
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Authors:
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Piotr Urbaniak; Paul Hasler; Samuel Kretzschmar |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2012-9-27 |
Journal Detail:
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Title: Clinical and experimental rheumatology Volume: - ISSN: 0392-856X ISO Abbreviation: Clin. Exp. Rheumatol. Publication Date: 2012 Sep |
Date Detail:
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Created Date: 2012-10-1 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8308521 Medline TA: Clin Exp Rheumatol Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Rheumaklinik und Institut für Physikalische Medizin und Rehabilitation, Kantonsspital Aarau AG, Aarau, Switzerland. piotr.urbaniak@ksa.ch. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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