Document Detail

Refraction-based 2D, 2.5D and 3D medical imaging: stepping forward to a clinical trial.
MedLine Citation:
PMID:  18620829     Owner:  NLM     Status:  MEDLINE    
An attempt at refraction-based 2D, 2.5D and 3D X-ray imaging of articular cartilage and breast carcinoma is reported. We are developing very high contrast X-ray 2D imaging with XDFI (X-ray dark-field imaging), X-ray CT whose data are acquired by DEI (diffraction-enhanced imaging) and tomosynthesis due to refraction contrast. 2D and 2.5D images were taken with nuclear plates or with X-ray films. Microcalcification of breast cancer and articular cartilage are clearly visible. 3D data were taken with an X-ray sensitive CCD camera. The 3D image was successfully reconstructed by the use of an algorithm newly made by our group. This shows a distinctive internal structure of a ductus lactiferi (milk duct) that contains inner wall, intraductal carcinoma and multifocal calcification in the necrotic core of the continuous DCIS (ductal carcinoma in situ). Furthermore consideration of clinical applications of these contrasts made us to try tomosynthesis. This attempt was satisfactory from the view point of articular cartilage image quality and the skin radiation dose.
Masami Ando; Hiroko Bando; Tokiko Endo; Shu Ichihara; Eiko Hashimoto; Kazuyuki Hyodo; Toshiyuki Kunisada; Gang Li; Anton Maksimenko; Kensaku Mori; Daisuke Shimao; Hiroshi Sugiyama; Tetsuya Yuasa; Ei Ueno
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2008-07-11
Journal Detail:
Title:  European journal of radiology     Volume:  68     ISSN:  1872-7727     ISO Abbreviation:  Eur J Radiol     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-12-01     Completed Date:  2009-04-06     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8106411     Medline TA:  Eur J Radiol     Country:  Ireland    
Other Details:
Languages:  eng     Pagination:  S32-6     Citation Subset:  IM    
Tokyo University of Science, Research Institute for Science and Technology, Noda, Chiba 278-8510, Japan.
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MeSH Terms
Breast Neoplasms / radiography*
Cartilage, Articular / radiography*
Clinical Trials as Topic
Imaging, Three-Dimensional / methods*
Radiographic Image Enhancement / methods*
Radiographic Image Interpretation, Computer-Assisted / methods
Refractometry / methods*
Reproducibility of Results
Sensitivity and Specificity
Tomography, X-Ray / methods*
Tomography, X-Ray Computed / methods*

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