Document Detail

Reflux monitoring: role of combined multichannel intraluminal impedance and pH.
MedLine Citation:
PMID:  15722247     Owner:  NLM     Status:  MEDLINE    
Combined multichannel intraluminal impedance and pH (MII-pH) is a promising technique that identifies liquid, gas, and mixed gastroesophageal reflux and categorizes it into acid and nonacid types. Gastroesophageal monitoring using combined MII-pH reconfirms previously reported data that there is a difference between refluxate volume presence time in the esophagus and time pH less than 4. Only one in five patients with persistent symptoms on acid-suppressive therapy have symptoms associated with persistent acid reflux, whereas two of five patients have symptoms associated with nonacid reflux; the remaining patients do not have any type of GER related to their symptoms. Combined MII-pH is a useful tool in evaluating patients with persistent symptoms on acid-suppressive therapy, patients with atypical symptoms, and infants.
Radu Tutuian; Donald O Castell
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Publication Detail:
Type:  Comparative Study; Journal Article; Review    
Journal Detail:
Title:  Gastrointestinal endoscopy clinics of North America     Volume:  15     ISSN:  1052-5157     ISO Abbreviation:  Gastrointest. Endosc. Clin. N. Am.     Publication Date:  2005 Apr 
Date Detail:
Created Date:  2005-02-21     Completed Date:  2005-04-20     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  9202792     Medline TA:  Gastrointest Endosc Clin N Am     Country:  United States    
Other Details:
Languages:  eng     Pagination:  361-71     Citation Subset:  IM    
Division of Gastroenterology/Hepatology, Medical University of South Carolina, 96 Jonathan Lucas Street, 210 CSB, Charleston, SC 29425, USA.
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MeSH Terms
Electric Impedance*
Esophagoscopy / methods
Gastroesophageal Reflux / diagnosis*
Hydrogen-Ion Concentration*
Manometry / methods
Monitoring, Ambulatory
Monitoring, Physiologic / instrumentation,  methods*
Risk Assessment
Sensitivity and Specificity
Severity of Illness Index

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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