| Reflux esophagitis and marginal ulcer after pancreaticoduodenectomy. | |
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MedLine Citation:
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PMID: 21347872 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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BACKGROUND: Reflux esophagitis is a common complication following a distal gastrectomy. Increasingly, Roux-en-Y reconstruction has been used to prevent reflux esophagitis; however, marginal ulcer is a concern in patients with a Roux-en-Y reconstruction after distal gastrectomy. The effect of Roux-en-Y reconstruction on the development of reflux esophagitis and marginal ulcer after pancreaticoduodenectomy (PD) has not been studied. METHODS: We retrospectively studied both reflux esophagitis and marginal ulcer after 371 PDs and analyzed the association with different methods of gastrointestinal reconstruction. RESULTS: In a median follow-up time of 20 months, 40 (10.8%) of the 371 patients developed reflux esophagitis, 15 after 158 standard PD, and 25 after 213 pylorus-preserving pancreaticoduodenectomy (PPPD; P = 0.62). Cox regression model showed Roux-en-Y reconstruction was significantly inversely related to occurrence of reflux esophagitis in 158 patients after standard PD (P = 0.04) but not in 213 patients after PPPD (P = 0.24). Thirty-five of 371 studied patients developed marginal ulcer, 15 after standard PD and 20 after PPPD (P = 0.45). Multivariate analysis showed that Roux-en-Y reconstruction was the only significant predictor for marginal ulcer after PD (P = 0.02). CONCLUSIONS: Our data support the use of Roux-en-Y reconstruction after standard PD but not after PPPD. |
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Authors:
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Jin-Ming Wu; Meng-Kun Tsai; Rey-Heng Hu; Kin-Jen Chang; Po-Huang Lee; Yu-Wen Tien |
Publication Detail:
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Type: Comparative Study; Journal Article Date: 2011-02-24 |
Journal Detail:
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Title: Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract Volume: 15 ISSN: 1873-4626 ISO Abbreviation: J. Gastrointest. Surg. Publication Date: 2011 May |
Date Detail:
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Created Date: 2011-04-22 Completed Date: 2011-09-22 Revised Date: 2012-02-29 |
Medline Journal Info:
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Nlm Unique ID: 9706084 Medline TA: J Gastrointest Surg Country: United States |
Other Details:
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Languages: eng Pagination: 824-8 Citation Subset: IM |
Affiliation:
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Department of Surgery, National Taiwan University Hospital, National Taiwan University College of Medicine, 7 Chung-Shan South Rd, 10002, Taipei, Taiwan, Republic of China. |
Export Citation:
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| MeSH Terms | |
Descriptor/Qualifier:
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Bile Duct Diseases
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surgery* Endoscopy, Gastrointestinal Esophagitis, Peptic / diagnosis, epidemiology, etiology* Female Follow-Up Studies Humans Incidence Male Middle Aged Pancreaticoduodenectomy / adverse effects Postoperative Complications Prognosis Retrospective Studies Stomach Ulcer / diagnosis, epidemiology, etiology* Taiwan / epidemiology |
| Comments/Corrections | |
Comment In:
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J Gastrointest Surg. 2012 Feb;16(2):452
[PMID:
22089953
]
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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