| Reflex writing seizures in two siblings with juvenile myoclonic epilepsy. | |
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MedLine Citation:
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PMID: 14763964 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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We report on two siblings who presented with juvenile myoclonic epilepsy, and in whom myoclonic jerks of the right arm and hand were also triggered by writing tasks. Both patients underwent intensive video-electroencephalography monitoring, with simultaneous neuropsychological tests. In both patients, reflex epileptic myoclonus was more easily triggered by writing that required a higher degree of concentration. Conversely, other cognitive tasks, such as reading, typing, thinking, or calculation never elicited any seizures or myoclonus. Valproate was effective in controlling both spontaneous and reflex epileptic seizures. The results of this study further support the notion that 'praxis-induced' reflex epilepsy precipitated by specific stimuli occurs in the context of idiopathic generalized epilepsy. Our results also illustrate that writing tasks are more effective in eliciting seizures when they require higher levels of concentration and mental elaboration. |
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Authors:
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R Chifari; A Piazzini; K Turner; R Canger; M P Canevini; P Wolf |
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Publication Detail:
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Type: Case Reports; Journal Article |
Journal Detail:
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Title: Acta neurologica Scandinavica Volume: 109 ISSN: 0001-6314 ISO Abbreviation: Acta Neurol. Scand. Publication Date: 2004 Mar |
Date Detail:
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Created Date: 2004-02-06 Completed Date: 2004-05-27 Revised Date: 2006-08-16 |
Medline Journal Info:
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Nlm Unique ID: 0370336 Medline TA: Acta Neurol Scand Country: Denmark |
Other Details:
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Languages: eng Pagination: 232-5 Citation Subset: IM |
Affiliation:
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Regional Centre of Epilepsy, San Paolo Hospital, Milan, Italy Epilepsy Center Bethel, Klinik MaraI, Bielefeld, Germany. rosanna.chifari@libero.it |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adolescent Adult Anticonvulsants / therapeutic use Attention / physiology Electroencephalography / drug effects Epilepsy, Reflex / diagnosis, drug therapy, genetics*, physiopathology Evoked Potentials / drug effects, physiology Female Handwriting Humans Myoclonic Epilepsy, Juvenile / diagnosis, drug therapy, genetics*, physiopathology Neuropsychological Tests Parietal Lobe / drug effects, physiopathology Psychomotor Performance / physiology Temporal Lobe / drug effects, physiopathology Treatment Outcome Valproic Acid / therapeutic use Video Recording |
| Chemical | |
Reg. No./Substance:
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0/Anticonvulsants; 99-66-1/Valproic Acid |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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