Document Detail

Refining the role of oxygen administration during delivery room resuscitation: what are the future goals?
MedLine Citation:
PMID:  18485848     Owner:  NLM     Status:  MEDLINE    
Oxygen was discovered more than 200 years ago and was thought to be both essential and beneficial for all animal life. Although it is now over 100 years since oxygen was first shown to damage biological tissues exposed to high concentrations, and more than 50 years since it was implicated in the aetiology of retinopathy of prematurity, the use of 100% oxygen was still recommended for the resuscitation of all babies at birth as recently as 2000. However, the 2005 International Liaison Committee on Resuscitation (ILCOR) recommendations allow for the initiation of resuscitation with concentrations of oxygen between 21 and 100%. There are strong arguments in favour of a radical curtailment of the use of oxygen in resuscitation at birth, and for devoting resources to defining the margins of safety for its use in the neonatal period in general.
Sam Richmond; Jay P Goldsmith
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Publication Detail:
Type:  Journal Article; Review     Date:  2008-05-15
Journal Detail:
Title:  Seminars in fetal & neonatal medicine     Volume:  13     ISSN:  1744-165X     ISO Abbreviation:  -     Publication Date:  2008 Dec 
Date Detail:
Created Date:  2008-10-20     Completed Date:  2009-02-10     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101240003     Medline TA:  Semin Fetal Neonatal Med     Country:  Netherlands    
Other Details:
Languages:  eng     Pagination:  368-74     Citation Subset:  IM    
Sunderland Royal Hospital, Sunderland SR4 7TP, UK.
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MeSH Terms
Asphyxia Neonatorum / therapy*
Delivery Rooms
Infant, Newborn
Oxygen Inhalation Therapy* / adverse effects
Resuscitation / methods*
Vascular Resistance

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