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Reference values of serum cystatin C in very low birth weight premature infants.
MedLine Citation:
PMID:  23016830     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
AIM: To determine reference values for cystatin C (CysC) and its correlation with creatinine (Cr), gestational age, birth weight and maternal Cr status in very low birth weight (VLBW) preterm infants. METHOD: The study included 113 VLBW premature infants (<1500 g) of ≤32 gestational week. Serum Cr and Cys C of the infant and serum Cr of the mother were analysed. RESULTS: The mean level of CysC was 1.77 ± 0.38 mg/L on day 1 and 1.61 ± 0.37 mg/L on day 3, and the decrease was statistically significant. There was a significant correlation only between maternal Cr and first-day Cr values and negative correlations between Cr and gestational age and birth weight on third day. Creatinine was not correlated with CysC both on day 1 (r=-0.077, p=0.417) and day 3 (r=0.132, p=0.164). CONCLUSION: Here we report the reference ranges for CysC and Cr on first and third day in VLBW infants. Cys C concentrations significantly decrease by day 3 compared to day 1 and are independent of gestational week, birth weight and maternal renal function status in VLBW preterm infants. © 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
Authors:
Gamze Demirel; Istemi Han Celik; Fuat Emre Canpolat; Omer Erdeve; Zeynep Biyikli; Ugur Dilmen
Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2012-9-27
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  Acta Paediatr.     Publication Date:  2012 Sep 
Date Detail:
Created Date:  2012-9-28     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
© 2012 The Author(s)/Acta Paediatrica © 2012 Foundation Acta Paediatrica.
Affiliation:
Division of Neonatology, Samsun Maternity and Child Health Hospital, Samsun, Turkey.
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