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Reference values for the Nocturnal Bladder Capacity Index.
MedLine Citation:
PMID:  20882675     Owner:  NLM     Status:  In-Process    
AIMS: The Nocturnal Bladder Capacity Index (NBCi) has been reported to be useful in distinguishing between nocturia caused by low bladder capacity and nocturnal polyuria. This paper aims to calculate reference values for NBCi from an asymptomatic population by comparing these with NBCi values from patients with lower urinary tract symptoms (LUTS) to obtain an indication of the sensitivity with which the NBCi detects low nocturnal bladder capacity. This paper also compares the sensitivity of rounded and unrounded calculations of NBCi.
METHODS: Computer processed 3-day bladder diaries from 253 asymptomatic volunteers and 184 female patients with LUTS were analyzed. NBCi values were calculated from each diary using rounded and unrounded formulae. 90th and 95th centile NBCi cutoff values were obtained from frequency distributions.
RESULTS: NBCi reference values from the asymptomatic group were 1.1 (unrounded) and 0.7 (rounded) for 90th centile, and 1.3 (unrounded) and 1.0 (rounded) for 95th centile. The use of the rounded formula gave identical NBCi values despite a large variation in V(n) /V(max) ratios whereas unrounded NBCis varied continuously with V(n) /V(max) ratios. The unrounded formula found significantly more elevated NBCis in the patient group.
CONCLUSION: We suggest that an unrounded NBCi of 1.3 be considered a cutoff point above which reduced nocturnal bladder capacity should be investigated as a cause of nocturia. Rounding the NBCi lead to an underestimation of elevated values in a population of female patients with LUTS.
Claire Burton; Jeffrey P Weiss; Matthew Parsons; Jerry G Blaivas; Alfred C Coats
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Publication Detail:
Type:  Journal Article     Date:  2010-09-29
Journal Detail:
Title:  Neurourology and urodynamics     Volume:  30     ISSN:  1520-6777     ISO Abbreviation:  Neurourol. Urodyn.     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2010-12-24     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  8303326     Medline TA:  Neurourol Urodyn     Country:  United States    
Other Details:
Languages:  eng     Pagination:  52-7     Citation Subset:  IM    
Copyright Information:
Copyright © 2010 Wiley-Liss, Inc.
Department of Urogynaecology, Birmingham Women's Hospital, Birmingham, UK.
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