| Reference intervals. | |
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MedLine Citation:
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PMID: 18852866 Owner: NLM Status: In-Data-Review |
Abstract/OtherAbstract:
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Recommended elements of a process for establishing a reference interval:Define the analyte (measurand) for which the reference interval is being established, the clinical utility, biological variation and major variations in form.Define the method used, the accuracy base, and analytical specificity.Define important pre-analytical considerations together with any actions in response to the interference.Define the principle behind the reference interval (i.e. central 95% etc.)DESCRIBE THE DATA SOURCE(S), INCLUDING: number of subjects, nature of subjects, exclusions, pre-analytical factors, statistical measures, outliers excluded and analytical method.Define considerations of partitioning based on age, sex etc.Define the number of significant figures, i.e. the degree of rounding.Define the clinical relevance of the reference limits.Consider the use of common reference intervals.Decision and implementation. |
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Authors:
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Graham Jones; Antony Barker |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: The Clinical biochemist. Reviews / Australian Association of Clinical Biochemists Volume: 29 Suppl 1 ISSN: 0159-8090 ISO Abbreviation: Clin Biochem Rev Publication Date: 2008 Aug |
Date Detail:
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Created Date: 2008-10-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8215797 Medline TA: Clin Biochem Rev Country: Australia |
Other Details:
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Languages: eng Pagination: S93-7 Citation Subset: - |
Affiliation:
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Department of Chemical Pathology, St Vincent's Hospital, Sydney, Victoria St, Darlinghurst, NSW 2010. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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