Document Detail

Reference interval of serum heat-stable alkaline phosphatase activity in pregnant women in Zaria.
MedLine Citation:
PMID:  16633376     Owner:  NLM     Status:  MEDLINE    
The study was designed to establish a reference interval for serum heat-stable ALP activity in pregnancy, which is not available in this environment. MATERIALS AND METHODS: One hundred (100) apparently healthy pregnant women in their third (3rd) trimester who were attending the antenatal clinic (ANC) of Ahmadu Bello University Teaching Hospital (ABUTH), Zaria were recruited for the study. The serum heat-stable ALP activity was measured using the 4-nitrophenyl phosphate (4-NPP) method introduced in 1946 by Bessey, Lowry and Brock. RESULTS: The reference interval for the serum heat-stable ALP activity was found to be 24-161 IU/L. This was similar to some earlier reports elsewhere. CONCLUSION: The finding will help in the evaluation/diagnosis of patients with placental insufficiency.
I S Aliyu; H S Isah; O A Afonja
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  The Nigerian postgraduate medical journal     Volume:  13     ISSN:  1117-1936     ISO Abbreviation:  Niger Postgrad Med J     Publication Date:  2006 Mar 
Date Detail:
Created Date:  2006-04-24     Completed Date:  2007-02-20     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9613595     Medline TA:  Niger Postgrad Med J     Country:  Nigeria    
Other Details:
Languages:  eng     Pagination:  31-4     Citation Subset:  IM    
Department of Chemical Pathology, Ahmadu Bello University Teaching Hospital, Zaria, Nigeria.
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MeSH Terms
Alkaline Phosphatase / blood*
Biological Markers / blood
Middle Aged
Pregnancy Trimester, Third / blood*
Reference Values
Reg. No./Substance:
0/Biological Markers; EC Phosphatase

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