| Reevaluation of micropuncture techniques: some of the factors which affect the rate of fluid absorption by the proximal tubule. | |
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MedLine Citation:
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PMID: 1192768 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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The present study has shown: (1) Hydrostatic pressure from the lumen is not an effective driving force ofr fluid absorption (Jv). (2) Hydrostatic pressure from the contraluminal side can strongly inhibit Jv. (3) Colloid in the capillary perfusate can effectively minimize the artifact of capillary perfusion. (4) HCO3 free serum as capillary perfusate inhibited Jv approximately to 50% of control. (5) 5 mM NaCN in capillary perfusate (dialyzed serum) inhibited Jv by 90% after two min and almost totally after 4 min. The presence or absence of exogenous substrate in capillary perfusate had no effect on NC-induced inhibition. The data indicate that glycolysis alone can not sustain fluid absorption. |
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Authors:
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K Sato |
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Publication Detail:
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Type: Journal Article |
Journal Detail:
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Title: Current problems in clinical biochemistry Volume: 4 ISSN: 0300-1725 ISO Abbreviation: Curr Probl Clin Biochem Publication Date: 1975 |
Date Detail:
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Created Date: 1976-02-09 Completed Date: 1976-02-09 Revised Date: 2003-11-14 |
Medline Journal Info:
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Nlm Unique ID: 0353507 Medline TA: Curr Probl Clin Biochem Country: SWITZERLAND |
Other Details:
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Languages: eng Pagination: 175-87 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Absorption Animals Bicarbonates / pharmacology Capillaries / metabolism Cyanides / pharmacology Energy Metabolism Glucose / metabolism Hydrostatic Pressure Kidney Tubules, Proximal / metabolism* Magnesium / metabolism Male Mannitol / pharmacology Models, Biological Perfusion / methods Potassium / metabolism Rats |
| Chemical | |
Reg. No./Substance:
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0/Bicarbonates; 0/Cyanides; 50-99-7/Glucose; 69-65-8/Mannitol; 7439-95-4/Magnesium; 7440-09-7/Potassium |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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