Document Detail

Reductions in salivary cortisol are associated with mood improvement during relaxation training among HIV-seropositive men.
MedLine Citation:
PMID:  10833675     Owner:  NLM     Status:  MEDLINE    
This study examined salivary cortisol and mood during relaxation training in 30 symptomatic, HIV+ gay men participating in a 10-week, group-based cognitive-behavioral stress management intervention. Cortisol levels and mood were assessed within these sessions just before and after 45-min relaxation exercises given as part of each session. Participants also recorded their stress level and compliance with daily home relaxation practice. Presession cortisol levels decreased across the 10-week period and were related to decreases in global measures of total mood disturbance and anxious mood. Reductions in presession cortisol levels were also associated with decreases in self-reported stress level during home practice. Greater reductions in cortisol during the first three sessions were associated with more frequent relaxation practice at home. These findings suggest that salivary cortisol represents an objective neuroendocrine marker for changes in anxiety and distress observed during relaxation training in symptomatic, HIV-seropositive men.
D G Cruess; M H Antoni; M Kumar; N Schneiderman
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Publication Detail:
Type:  Clinical Trial; Controlled Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Journal of behavioral medicine     Volume:  23     ISSN:  0160-7715     ISO Abbreviation:  J Behav Med     Publication Date:  2000 Apr 
Date Detail:
Created Date:  2000-08-10     Completed Date:  2000-08-10     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  7807105     Medline TA:  J Behav Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  107-22     Citation Subset:  IM; X    
Department of Psychology, University of Miami, Coral Gables, Florida 33124-2070, USA.
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MeSH Terms
Anxiety / etiology
CD4 Lymphocyte Count
HIV Seropositivity / complications*
Hydrocortisone / metabolism*
Middle Aged
Mood Disorders / complications,  metabolism*,  therapy*
Psychological Tests
Relaxation Therapy*
Saliva / metabolism*
Social Class
Treatment Outcome
Grant Support
Reg. No./Substance:

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