Document Detail


Reductions in medications with substantial weight loss with behavioral intervention.
MedLine Citation:
PMID:  20925648     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Medical costs of obesity in the United States exceed $147 billion annually with medication costs making a sizable contribution. We examined medication costs associated with substantial weight losses in an intensive behavioral weight loss program. Inclusion criteria were medication use for obesity co-morbidities: hypertension, diabetes, dyslipidemia, degenerative joint disease, or gastroesophageal reflux disease. Group A, 83 obese patients on medications completed 8 weeks of classes, lost 19 kg in 20 weeks. Group B, 100 severely obese patients, lost 59 kg in 45 weeks. Medications were discontinued: Group A, 18%; Group B, 64%. Mean numbers of medications decreased significantly for all co-morbidities. Mean numbers of daily medications, initial and final, respectively were: Group A, total, 3.0 ± 0.2 (mean ± SEM) and 1.7 ± 0.2; Group B, total, 2.5 ± 0.2 and 0.7 ± 0.1. Monthly costs for all medications decreased significantly for all co-morbidities and were as follows: Group A, total, $249 ± 25 and $153 ± 19; Group B: total, $237 ± 27 and $65 ± 12. Medically supervised weight loss is very effective approach for improving cardiovascular risk factors and reducing medical costs.
Authors:
James W Anderson; Manan A Jhaveri
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't; Review    
Journal Detail:
Title:  Current clinical pharmacology     Volume:  5     ISSN:  1574-8847     ISO Abbreviation:  Curr Clin Pharmacol     Publication Date:  2010 Nov 
Date Detail:
Created Date:  2010-11-12     Completed Date:  2011-03-01     Revised Date:  2011-09-06    
Medline Journal Info:
Nlm Unique ID:  101273158     Medline TA:  Curr Clin Pharmacol     Country:  United Arab Emirates    
Other Details:
Languages:  eng     Pagination:  232-8     Citation Subset:  IM    
Affiliation:
Department of Internal Medicine and Clinical Nutrition, University of Kentucky, 913 Taborlake Court, Lexington, KY 40502, USA. jwandersmd@aol.com
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MeSH Terms
Descriptor/Qualifier:
Antihypertensive Agents / economics,  therapeutic use
Behavior Therapy*
Diabetes Mellitus / drug therapy,  economics
Drug Costs / statistics & numerical data*
Dyslipidemias / economics,  prevention & control
Humans
Hypertension / drug therapy,  economics
Hypoglycemic Agents / economics,  therapeutic use
Hypolipidemic Agents / economics,  therapeutic use
Obesity / economics*,  psychology*
Risk Factors
Weight Loss*
Chemical
Reg. No./Substance:
0/Antihypertensive Agents; 0/Hypoglycemic Agents; 0/Hypolipidemic Agents

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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