| Reduction of side effects by combining clozapine with amisulpride: case report and short review of clozapine-induced hypersalivation-a case report. | |
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MedLine Citation:
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PMID: 15706466 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Side effects from a high-dose clozapine treatment for a schizophrenic patient led to massive compliance problems. The dose of clozapine could be halved without recurrence of an acute psychotic symptomatology by concomitantly administering amisulpride. The side effects, especially hypersalivation, disappeared almost entirely, which in turn led to good compliance. In a short review we would like to present the pathophysiology and therapeutic options of clozapine-induced hypersalivation. |
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Authors:
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B Croissant; D Hermann; R Olbrich |
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Publication Detail:
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Type: Case Reports; Letter |
Journal Detail:
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Title: Pharmacopsychiatry Volume: 38 ISSN: 0176-3679 ISO Abbreviation: Pharmacopsychiatry Publication Date: 2005 Jan |
Date Detail:
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Created Date: 2005-02-11 Completed Date: 2005-05-16 Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8402938 Medline TA: Pharmacopsychiatry Country: Germany |
Other Details:
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Languages: eng Pagination: 38-9 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Antipsychotic Agents / administration & dosage, adverse effects*, therapeutic use Clozapine / administration & dosage, adverse effects*, therapeutic use Drug Therapy, Combination Humans Male Schizophrenia, Paranoid / drug therapy, psychology Sialorrhea / chemically induced* Sulpiride / administration & dosage, adverse effects*, analogs & derivatives*, therapeutic use |
| Chemical | |
Reg. No./Substance:
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0/Antipsychotic Agents; 15676-16-1/Sulpiride; 53583-79-2/sultopride; 5786-21-0/Clozapine |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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