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Reduction of prostate intrafraction motion using gas-release rectal balloons.
MedLine Citation:
PMID:  23039625     Owner:  NLM     Status:  In-Data-Review    
Purpose: To analyze prostate intrafraction motion using both non-gas-release (NGR) and gas-release (GR) rectal balloons and to evaluate the ability of GR rectal balloons to reduce prostate intrafraction motion.Methods: Twenty-nine patients with NGR rectal balloons and 29 patients with GR balloons were randomly selected from prostate patients treated with proton therapy at the University of Florida Proton Therapy Institute (Jacksonville, FL). Their pretreatment and post-treatment orthogonal radiographs were analyzed, and both pretreatment setup residual error and intrafraction-motion data were obtained. Population histograms of intrafraction motion were plotted for both types of balloons. Population planning target-volume (PTV) margins were calculated with the van Herk formula of 2.5Σ + 0.7σ to account for setup residual errors and intrafraction motion errors.Results: Pretreatment and post-treatment radiographs indicated that the use of gas-release rectal balloons reduced prostate intrafraction motion along superior-inferior (SI) and anterior-posterior (AP) directions. Similar patient setup residual errors were exhibited for both types of balloons. Gas-release rectal balloons resulted in PTV margin reductions from 3.9 to 2.8 mm in the SI direction, 3.1 to 1.8 mm in the AP direction, and an increase from 1.9 to 2.1 mm in the left-right direction.Conclusions: Prostate intrafraction motion is an important uncertainty source in radiotherapy after image-guided patient setup with online corrections. Compared to non-gas-release rectal balloons, gas-release balloons can reduce prostate intrafraction motion in the SI and AP directions caused by gas buildup.
Zhong Su; Tianyu Zhao; Zuofeng Li; Brad Hoppe; Randy Henderson; William Mendenhall; R Charles Nichols; Robert Marcus; Nancy Mendenhall
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Medical physics     Volume:  39     ISSN:  0094-2405     ISO Abbreviation:  Med Phys     Publication Date:  2012 Oct 
Date Detail:
Created Date:  2012-10-08     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  0425746     Medline TA:  Med Phys     Country:  United States    
Other Details:
Languages:  eng     Pagination:  5869-73     Citation Subset:  IM    
Department of Radiation Oncology, University of Florida Proton Therapy Institute, Jacksonville, Florida 32206.
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