Document Detail

Reduction of postnatal cumulative nutritional deficit and improvement of growth in extremely preterm infants.
MedLine Citation:
PMID:  21854447     Owner:  NLM     Status:  Publisher    
Aim:  To evaluate the influence of gestational age on cumulative nutritional deficit and postnatal growth in extremely preterm infants after optimizing nutritional protocol as recently recommended. Methods:  A prospective non randomized observational study in extremely preterm (EPT,<28 wks) and very preterm (VPT,28-30wks) infants. Results:  84 infants were included (BW: 978 ±156g, GA: 27.8 ±1.3wks). Cumulative nutritional deficit increased during first week of life to -290 ±84 and -285 ±117 kcal/kg and -4.2 ±3.1 and -4.8 ±3.9 g/kg of protein in EPT and VPT groups respectively. After 6 weeks, only cumulative energy deficit in EPT group remained significant (p<0.05) even when 96% of theoretical energy intakes were provided. Weight z score decreased during first 3 days in average with initial weight loss, then the z score increased during the first 6 weeks of life in the majority (75%) of infants. Cumulative protein deficit during the first week of life was the major determinant of the postnatal growth during the first 6 weeks of life. Conclusion:  Cumulative nutritional deficit may be drastically reduced in both EPT and VPT infants after optimizing nutritional policy during the first weeks of life and postnatal growth restriction could even be prevented.
Thibault Senterre; Jacques Rigo
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-8-20
Journal Detail:
Title:  Acta paediatrica (Oslo, Norway : 1992)     Volume:  -     ISSN:  1651-2227     ISO Abbreviation:  -     Publication Date:  2011 Aug 
Date Detail:
Created Date:  2011-8-22     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9205968     Medline TA:  Acta Paediatr     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Copyright Information:
Acta Paediatrica © 2011 Foundation Acta Paediatrica.
Department of Neonatology, University of Liege, CHU de Liège, CHR de la Citadelle, Liège, Belgium.
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