Document Detail

Reduction of lipoprotein (a) by weight loss.
MedLine Citation:
PMID:  2401585     Owner:  NLM     Status:  MEDLINE    
Lipoprotein (a) is believed to be an independent risk factor for atherosclerosis. Fat modified diets or lipid lowering drugs seem to have little effect on Lp(a) serum levels. We tested the possibility of lowering Lp(a) by weight reduction and examined the correlation between Lp(a) serum levels, other lipoproteins, body weight and body fat distribution in 53 obese patients. Weight reduction by a 4000 kJ protein enriched diet for four weeks led to a mean 19 percent reduction of Lp(a) serum levels in men (P less than 0.01) and a mean 30 percent reduction in premenopausal women (P less than 0.001). Significant correlations could neither be demonstrated between Lp(a) and other lipoproteins nor between initial Lp(a), overweight and body fat distribution. This implies that an intraindividual interdependence between Lp(a) and body weight seems to be possible although an interindividual correlation can not be shown.
A C Sönnichsen; W O Richter; P Schwandt
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  International journal of obesity     Volume:  14     ISSN:  -     ISO Abbreviation:  Int J Obes     Publication Date:  1990 Jun 
Date Detail:
Created Date:  1990-10-24     Completed Date:  1990-10-24     Revised Date:  2014-06-03    
Medline Journal Info:
Nlm Unique ID:  7703240     Medline TA:  Int J Obes     Country:  ENGLAND    
Other Details:
Languages:  eng     Pagination:  487-94     Citation Subset:  IM    
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MeSH Terms
Adipose Tissue / anatomy & histology
Body Composition
Diet, Reducing
Food, Formulated
Lipids / blood
Lipoproteins / blood*
Middle Aged
Obesity / blood*,  diet therapy
Weight Loss*
Reg. No./Substance:
0/Lipids; 0/Lipoproteins

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