Document Detail


Reduction in urinary oxalate values by allopurinol.
MedLine Citation:
PMID:  695155     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
A variety of substances have been used to prevent recurrence of stone disease. Recently there has been considerable interest in the ability of allopurinol to prevent stone recurrence. This article discusses the effect of allopurinol on the urinary oxalate in a group of stone formers. A significant reduction was obtained especially in subjects in whom the blood urate levels exceeded 300 mumol./L. Possible mechanisms explaining the mode of action of the drug are discussed.
Authors:
R Scott; P J Paterson; M Smith; A Mathieson
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  Urology     Volume:  12     ISSN:  0090-4295     ISO Abbreviation:  Urology     Publication Date:  1978 Aug 
Date Detail:
Created Date:  1978-11-22     Completed Date:  1978-11-22     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0366151     Medline TA:  Urology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  212-4     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adult
Aged
Allopurinol / pharmacology*,  therapeutic use
Calcium / urine
Female
Humans
Male
Middle Aged
Oxalates / urine*
Urinary Calculi / drug therapy,  prevention & control*
Chemical
Reg. No./Substance:
0/Oxalates; 315-30-0/Allopurinol; 7440-70-2/Calcium

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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