Document Detail

Reduction in resting end-expiratory position of the respiratory system with induction of anesthesia and neuromuscular paralysis.
MedLine Citation:
PMID:  7091715     Owner:  NLM     Status:  MEDLINE    
Resting end-expiratory position (REEP) of the respiratory system was monitored continuously using spirometric recording in eleven patients during transition from consciousness to thiopental hypnosis and following subsequent administration of succinylcholine. REEP decreased following thiopental and was little affected by subsequent relaxant in most patients. A fall in REEP was observed within 30 s after thiopental, and a lower, stable level of REEP was attained within approximately 15-45 s. Mean volume of gas expelled from the lungs was 189 (SE 32) ml BTPS. It is concluded that the previously extensively documented decrease in functional residual capacity associated with anesthesia occurs immediately on induction and requires a short, but finite, time for apparent stabilization.
N A Bergman
Related Documents :
9669005 - Neuromuscular blocking effects of rocuronium during desflurane, isoflurane, and sevoflu...
25045715 - Heart health risk assessment system: a nonintrusive proposal using ontologies and exper...
3213395 - Continuous measurement of pulmonary gas exchange during general anaesthesia in man.
12419715 - Duration of control stimulation does not affect onset and offset of neuromuscular block...
6867355 - Coronary artery disease: detection by phase analysis of rest/exercise radionuclide angi...
19767815 - Postexercise rehydration in man: the effects of carbohydrate content and osmolality of ...
Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesiology     Volume:  57     ISSN:  0003-3022     ISO Abbreviation:  Anesthesiology     Publication Date:  1982 Jul 
Date Detail:
Created Date:  1982-08-07     Completed Date:  1982-08-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1300217     Medline TA:  Anesthesiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  14-7     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Anesthesia, General*
Functional Residual Capacity*
Lung Volume Measurements*
Middle Aged
Neuromuscular Depolarizing Agents / pharmacology*
Respiratory Physiological Phenomena
Spirometry / methods
Succinylcholine / pharmacology
Time Factors
Reg. No./Substance:
0/Neuromuscular Depolarizing Agents; 306-40-1/Succinylcholine; 76-75-5/Thiopental

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Endorphin levels in cerebrospinal fluid of patients with postoperative and chronic pain.
Next Document:  Effects of droperidol on left ventricular performance in humans.