Document Detail


Reduction in resting end-expiratory position of the respiratory system with induction of anesthesia and neuromuscular paralysis.
MedLine Citation:
PMID:  7091715     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Resting end-expiratory position (REEP) of the respiratory system was monitored continuously using spirometric recording in eleven patients during transition from consciousness to thiopental hypnosis and following subsequent administration of succinylcholine. REEP decreased following thiopental and was little affected by subsequent relaxant in most patients. A fall in REEP was observed within 30 s after thiopental, and a lower, stable level of REEP was attained within approximately 15-45 s. Mean volume of gas expelled from the lungs was 189 (SE 32) ml BTPS. It is concluded that the previously extensively documented decrease in functional residual capacity associated with anesthesia occurs immediately on induction and requires a short, but finite, time for apparent stabilization.
Authors:
N A Bergman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't    
Journal Detail:
Title:  Anesthesiology     Volume:  57     ISSN:  0003-3022     ISO Abbreviation:  Anesthesiology     Publication Date:  1982 Jul 
Date Detail:
Created Date:  1982-08-07     Completed Date:  1982-08-07     Revised Date:  2008-11-21    
Medline Journal Info:
Nlm Unique ID:  1300217     Medline TA:  Anesthesiology     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  14-7     Citation Subset:  AIM; IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Anesthesia, General*
Female
Functional Residual Capacity*
Humans
Lung Volume Measurements*
Male
Middle Aged
Neuromuscular Depolarizing Agents / pharmacology*
Respiratory Physiological Phenomena
Spirometry / methods
Succinylcholine / pharmacology
Thiopental
Time Factors
Chemical
Reg. No./Substance:
0/Neuromuscular Depolarizing Agents; 306-40-1/Succinylcholine; 76-75-5/Thiopental

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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