Document Detail


Reduction in colloid osmotic pressure associated with fatal progression of cardiopulmonary failure.
MedLine Citation:
PMID:  1181096     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
The relationship between colloid osmotic pressure (COP) and the severity of cardiopulmonary failure was investigated in 99 consecutive patients admitted to our Shock Unit including 41 survivors and 58 fatal cases. The COP was significantly lower (p less than 0.001) in fatal cases in comparison to survivors. None of 21 patients in whom COP was less than 10.5 torr survived. A progressive increase in survival with typical S-shaped distribution was observed as COP increased from 10 to 19 torr, above which all patients survived. These preliminary observations demonstrated that reduction in COP in critically ill patients is associated with increases in mortality. The mechanisms by which lowering of COP may be related to fatal progression of cardiopulmonary failure is the subject of continuing study.
Authors:
M Morissette; M H Weil; H Shubin
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Publication Detail:
Type:  Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.    
Journal Detail:
Title:  Critical care medicine     Volume:  3     ISSN:  0090-3493     ISO Abbreviation:  Crit. Care Med.     Publication Date:    1975 May-Jun
Date Detail:
Created Date:  1976-01-08     Completed Date:  1976-01-08     Revised Date:  2006-11-15    
Medline Journal Info:
Nlm Unique ID:  0355501     Medline TA:  Crit Care Med     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  115-7     Citation Subset:  IM    
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Aged
Capillary Permeability*
Female
Humans
Male
Middle Aged
Osmotic Pressure
Prognosis
Shock / mortality,  physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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