| Reduction in cardiovascular risk by sodium-bicarbonated mineral water in moderately hypercholesterolemic young adults. | |
| | |
MedLine Citation:
|
PMID: 19954956 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
The effects of drinking sodium-bicarbonated mineral water on cardiovascular risk in young men and women with moderate cardiovascular risk were studied. Eighteen young volunteers (total cholesterol levels >5.2 mmol/L) without any disease participated. The study consisted of two 8-week intervention periods. Subjects consumed, as supplement to their usual diet, 1 L/day control low mineral water, followed by 1 L/day bicarbonated mineral water (48 mmol/L sodium, 35 mmol/L bicarbonate and 17 mmol/L chloride). Determinations were performed at the end of the control water period and on Weeks 4 and 8 of the bicarbonated water period. Body weight, body mass index (BMI), blood pressure, dietary intake, total cholesterol, low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, apolipoprotein (Apo) A-I, Apo B, triacylgycerols, glucose, insulin, adiponectin, high-sensitivity C-reactive protein (hs-CRP), soluble adhesion molecules [soluble intercellular adhesion molecule (sICAM) and soluble vascular adhesion molecule (sVCAM)], sodium and chloride urinary excretion, and urine pH were measured. Dietary intake, body weight and BMI showed no significant variations. Systolic blood pressure decreased significantly after 4 weeks of bicarbonated water consumption, without significant differences between Weeks 4 and 8. After bicarbonated water consumption, significant reductions in total cholesterol (by 6.3%; P=.012), LDL cholesterol (by 10%; P=.001), total/HDL cholesterol (P=.004), LDL/HDL cholesterol (P=.001) and Apo B (P=.017) were observed. Serum triacylglycerol, Apo A-I, sICAM-1, sVCAM-1 and hs-CRP levels did not change. Serum glucose values tended to decrease during the bicarbonated water intervention (P=.056), but insulin levels did not vary. This sodium-bicarbonated mineral water improves lipid profile in moderately hypercholesterolemic young men and women and could therefore be applied in dietary interventions to reduce cardiovascular risk. |
| | |
Authors:
|
Ana M Pérez-Granados; Santiago Navas-Carretero; Stefanie Schoppen; M Pilar Vaquero |
Related Documents
:
|
9481526 - A diet rich in walnuts favourably influences plasma fatty acid profile in moderately hy... 19835106 - Cholesterol levels in later life amongst uk channel islanders exposed to the 1940-45 ge... 3379136 - Treatment of obese, diet-restricted subjects with growth hormone for 11 weeks: effects ... 20402316 - Are lipoprotein disturbances in chronic hemodialyzed patients only renal failure related? 15331886 - Elimination and tolerance of a new parenteral lipid emulsion (smof)--a double-blind cro... 16154606 - Effects of alternations (10 days) of high-fat with normal diet on liver lipid infiltrat... |
Publication Detail:
|
Type: Journal Article; Research Support, Non-U.S. Gov't Date: 2009-12-01 |
Journal Detail:
|
Title: The Journal of nutritional biochemistry Volume: 21 ISSN: 1873-4847 ISO Abbreviation: J. Nutr. Biochem. Publication Date: 2010 Oct |
Date Detail:
|
Created Date: 2010-09-20 Completed Date: 2011-01-28 Revised Date: - |
Medline Journal Info:
|
Nlm Unique ID: 9010081 Medline TA: J Nutr Biochem Country: United States |
Other Details:
|
Languages: eng Pagination: 948-53 Citation Subset: IM |
Copyright Information:
|
Copyright © 2010 Elsevier Inc. All rights reserved. |
Affiliation:
|
Department of Metabolism and Nutrition, Instituto del Frío, Institute of Food Science and Technology and Nutrition, Spanish National Research Council, 28040 Madrid, Spain. |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Adult Cardiovascular Diseases / etiology, prevention & control* Cholesterol / blood, classification Female Humans Hypercholesterolemia / complications* Male Mineral Waters* Risk Reduction Behavior Sodium Bicarbonate* |
| Chemical | |
Reg. No./Substance:
|
144-55-8/Sodium Bicarbonate; 57-88-5/Cholesterol |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Dietary fish oil n-3 polyunsaturated fatty acids and alpha-linolenic acid differently affect brain a...
Next Document: Mechanisms of anti-atherosclerotic functions of soy-based diets.