Document Detail

Reduction in arterial distensibility in hypertensive patients as evaluated by ambulatory measurement of the QKD interval is correlated with concentric remodeling of the left ventricle.
MedLine Citation:
PMID:  10619589     Owner:  NLM     Status:  MEDLINE    
Relationships between ambulatory arterial pressure and arterial distensibility as assessed by ambulatory measure of the QKD interval and echocardiographic measurement of left ventricular mass and relative wall thickness were evaluated in a population of 163 untreated hypertensive patients. The height-corrected QKD100-60 interval was significantly correlated with left ventricular mass (LVM; r = -0.29, P<.001) and with relative wall thickness (r = -0.31, P<0.001). In a multivariate analysis, LVM was significantly correlated with mean arterial pressure, pulse pressure, and age, whereas the relative wall thickness was correlated with the QKD interval and the mean arterial pressure. The concentric character of the LVH of the hypertensive patient was thus linked to the reduction in arterial distensibility.
P Gosse; V Jullien; P Jarnier; P Lemetayer; J Clementy
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Publication Detail:
Type:  Comparative Study; Journal Article    
Journal Detail:
Title:  American journal of hypertension     Volume:  12     ISSN:  0895-7061     ISO Abbreviation:  Am. J. Hypertens.     Publication Date:  1999 Dec 
Date Detail:
Created Date:  2000-01-20     Completed Date:  2000-01-20     Revised Date:  2009-02-24    
Medline Journal Info:
Nlm Unique ID:  8803676     Medline TA:  Am J Hypertens     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  1252-5     Citation Subset:  IM    
Hôpital Saint André, Bordeaux, France.
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MeSH Terms
Blood Pressure / physiology*
Blood Pressure Monitoring, Ambulatory*
Brachial Artery / physiopathology*
Circadian Rhythm
Electrocardiography, Ambulatory*
Heart Ventricles / physiopathology*,  ultrasonography
Hypertension / physiopathology*,  ultrasonography
Middle Aged
Vascular Resistance / physiology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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