Document Detail

A reduction in body mass index lowers risk for bilateral slipped capital femoral epiphysis.
MedLine Citation:
PMID:  23378238     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: Slipped capital femoral epiphysis (SCFE) is occurring in greater numbers, at increasingly younger ages, and more frequently bilaterally (BL-SCFE). Obesity is one risk factor for SCFE. However, it is unclear whether postoperative decreases or increases in body mass index (BMI) alter the risk of subsequent contralateral SCFE.
QUESTIONS/PURPOSES: We therefore determined whether (1) BMI percentile was a risk factor for BL-SCFE; and (2) postoperative increases and/or decreases in BMI percentile influenced the risk for BL-SCFE.
METHODS: We retrospectively reviewed the records of 502 patients surgically treated for SCFE and identified 138 (27%) with BL-SCFE and 364 (73%) with unilateral SCFE (UL-SCFE); 173 patients, 60 (35%) with BL-SCFE and 113 (65%) with UL-SCFE met our inclusion criteria. Risk factors included sex, age, slip stability, slip chronicity, slip angle, and obesity. Percentile BMI was recorded at the time of first SCFE surgery, at the time of last followup for patients undergoing UL-SCFE, and at the time of second SCFE surgery for patients undergoing BL-SCFE.
RESULTS: Sex, age, slip stability, and slip angle were not associated with BL-SCFE. Postoperative obesity (odds ratio [OR], 3.5; 95% confidence interval [CI], 1.2-9.7) and acute slip chronicity (OR, 2.9; 95% CI, 1.3-6.7) had higher risks for sequential BL-SCFE. Obese patients who became nonobese postoperatively had a decreased risk of sequential BL-SCFE compared with those who remained obese (OR, 0.16; 95% CI, 1.2-116.5).
CONCLUSIONS: Only postoperative obesity and an acute slip were risk factors for sequential BL-SCFE. BMI reduction to lower than the 95% percentile after SCFE surgery was associated with lower risk for BL-SCFE development. The data suggest early supervised therapeutic weight management programs for patients treated for UL-SCFE are important to reduce risk of subsequent SCFE.
LEVEL OF EVIDENCE: Level III, prognostic study. See Guidelines for Authors for a complete description of levels of evidence.
Adam Y Nasreddine; Benton E Heyworth; David Zurakowski; Mininder S Kocher
Related Documents :
24296808 - Prevalence and associated factors of t-score discordance between different sites in ira...
24970328 - Clinical and epidemiological characteristics of individuals resistant to m. tuberculosi...
24557448 - Childhood violence exposure and the development of sexual risk in low-income african am...
23976898 - Ocular adnexal non-hodgkin's lymphoma: a review of epidemiology and risk factors.
12454698 - Enhanced risk of thrombotic disease in patients with acquired vitamin b12 and/or folate...
22377228 - Theories of urinary incontinence causation: aetiological descriptions by sub-saharan af...
Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Clinical orthopaedics and related research     Volume:  471     ISSN:  1528-1132     ISO Abbreviation:  Clin. Orthop. Relat. Res.     Publication Date:  2013 Jul 
Date Detail:
Created Date:  2013-06-10     Completed Date:  2013-08-28     Revised Date:  2014-07-01    
Medline Journal Info:
Nlm Unique ID:  0075674     Medline TA:  Clin Orthop Relat Res     Country:  United States    
Other Details:
Languages:  eng     Pagination:  2137-44     Citation Subset:  AIM; IM    
Export Citation:
APA/MLA Format     Download EndNote     Download BibTex
MeSH Terms
Biomechanical Phenomena
Body Mass Index*
Hip Joint / physiopathology,  radiography,  surgery*
Kaplan-Meier Estimate
Logistic Models
Multivariate Analysis
Obesity / complications,  diagnosis,  therapy*
Odds Ratio
Orthopedic Procedures* / adverse effects
Postoperative Complications / etiology,  prevention & control*
Retrospective Studies
Risk Assessment
Risk Factors
Slipped Capital Femoral Epiphyses / diagnosis,  etiology,  physiopathology,  surgery*
Time Factors
Treatment Outcome
Weight Loss*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

Previous Document:  Transforming growth factor-?1 treatment of oral cancer induces epithelial-mesenchymal transition and...
Next Document:  CORR insights: Orthopaedic residency applications increase after implementation of 80-hour workweek.