| Reduction of gray matter density in the extrastriate body area in women with anorexia nervosa. | |
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MedLine Citation:
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PMID: 19729041 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Body processing has been associated functionally to the so called extrastriate body area (EBA) which is located in the lateral occipital cortex. As body image disturbance is one of the main diagnostic criteria in anorexia nervosa (AN) this study aimed at looking for alterations in gray matter density in women with (AN) especially in the EBA. High resolution T1 images from 15 women with AN and 15 age matched healthy controls women were contrasted using voxel based morphometry (VBM). Additionally functional localizer scans were used to determine functionally the EBA of each participant. In general, total gray matter volumes did differ between groups. VBM results yielded evidence for a reduction of gray matter density in the left EBA. This reduction, which resulted from whole brain analysis, was localised within the activation cluster of the EBA localizer scan. The current results provide for the first time evidence for structural alterations in the EBA in patients with AN which might suggest that body image distortion is related at least in part to structural alteration in the EBA. |
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Authors:
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Boris Suchan; Martin Busch; Dietmar Schulte; Dietrich Grönemeyer; Dietrich Grönermeyer; Stephan Herpertz; Silja Vocks |
Publication Detail:
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Type: Journal Article Date: 2009-09-01 |
Journal Detail:
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Title: Behavioural brain research Volume: 206 ISSN: 1872-7549 ISO Abbreviation: Behav. Brain Res. Publication Date: 2010 Jan |
Date Detail:
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Created Date: 2009-10-28 Completed Date: 2009-12-09 Revised Date: 2011-01-11 |
Medline Journal Info:
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Nlm Unique ID: 8004872 Medline TA: Behav Brain Res Country: Netherlands |
Other Details:
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Languages: eng Pagination: 63-7 Citation Subset: IM |
Affiliation:
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Institute of Cognitive Neuroscience, Department of Neuropsychology, Ruhr-University Bochum, Bochum, Germany. Boris.Suchan@rub.de |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adult Analysis of Variance Anorexia Nervosa / pathology*, physiopathology* Brain Mapping Female Humans Image Processing, Computer-Assisted Magnetic Resonance Imaging Neuropsychological Tests Occipital Lobe / pathology*, physiopathology* Organ Size |
| Comments/Corrections | |
Erratum In:
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Behav Brain Res. 2011 Mar 1;217(2):488 Note: Grönermeyer, Dietrich [corrected to Grönemeyer, Dietrich] |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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