| Reducing vasomotor symptoms with acupuncture in breast cancer patients treated with adjuvant tamoxifen: a randomized controlled trial. | |
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MedLine Citation:
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PMID: 21153699 Owner: NLM Status: Publisher |
Abstract/OtherAbstract:
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To evaluate true acupuncture to control acupuncture (CTRL) (non-insertive stimulation at non-acupuncture points) in breast cancer patients treated with adjuvant tamoxifen suffering from hot flushes and sweatings. Eighty-four patients were randomized to receive either true acupuncture or CTRL twice a week for 5 weeks. Seventy-four patients were treated according to the protocol. In the true acupuncture group 42% (16/38) reported improvements in hot flushes after 6 weeks compared to 47% (17/36) in the CTRL group (95% CI, -28 to 18%). Both groups reported improvement regarding severity and frequencies in hot flushes and sweatings but no statistical difference was found between the groups. In a subanalysis regarding the severity of sweatings at night a statistically significant difference P = 0.03 was found in the true acupuncture group. Former experience of true acupuncture did not influence the perception of true acupuncture or CTRL. No significant differences in hormonal levels were found before and after treatment. In conclusion, convincing data that true acupuncture is more effective than CTRL in reducing vasomotor symptoms is still lacking. Our study shows that both true and CTRL reduce vasomotor symptoms in breast cancer patients treated with adjuvant tamoxifen. |
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Authors:
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Annelie Liljegren; Pia Gunnarsson; Britt-Marie Landgren; Ninna Robéus; Hemming Johansson; Samuel Rotstein |
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Publication Detail:
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Type: JOURNAL ARTICLE Date: 2010-12-14 |
Journal Detail:
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Title: Breast cancer research and treatment Volume: - ISSN: 1573-7217 ISO Abbreviation: - Publication Date: 2010 Dec |
Date Detail:
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Created Date: 2010-12-14 Completed Date: - Revised Date: - |
Medline Journal Info:
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Nlm Unique ID: 8111104 Medline TA: Breast Cancer Res Treat Country: - |
Other Details:
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Languages: ENG Pagination: - Citation Subset: - |
Affiliation:
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Department of Oncology, Radiumhemmet, Karolinska University Hospital and Karolinska Institutet, 171 76, Stockholm, Sweden, annelie.liljegren@karolinska.se. |
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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