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Reducing postnatal depression, anxiety and stress using an infant sleep intervention.
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PMID:  22983788     Owner:  NLM     Status:  PubMed-not-MEDLINE    
OBJECTIVE: To examine the psychological well-being of mothers following participation in a behavioural modification programme previously shown to improve infant sleep.
DESIGN, SETTING AND PARTICIPANTS: A 45 min consultation with either a general practitioner (GP) or trained nurse providing verbal and written information describing sleep physiology in infants and strategies to improve infant sleep. Eighty mothers of infants 6-12 months of age with established infant sleep problems at a single general practice, Adelaide, South Australia.
MAIN OUTCOME MEASURES: The Depression Anxiety Stress Scale 21 (DASS21) immediately prior to the first consultation and again at follow-up approximately 3 weeks later. The number of infant nocturnal awakenings requiring parental support was also reported by mothers on both occasions.
RESULTS: All measures of maternal well-being and infant nocturnal awakenings improved significantly. The mean number of maximum nocturnal awakenings decreased from 5.0 to 0.5 (mean difference 4.4, 95% CI 3.4 to 5.5). All measures of DASS21 improved significantly. The mean total DASS21 decreased from 29.1 to 14.9 (mean decrease 14.2, 95% CI 10.2 to 18.2); mean depression decreased from 7.9 to 2.8 (mean difference 5.2, 95% CI 3.7 to 6.7); mean anxiety decreased from 4.6 to 2.6 (mean difference 2.0, 95% CI 0.7 to 3.2); mean stress decreased from 16.6 to 9.5 (mean difference 7.0, 95% CI 5.1 to 9.0). The proportion of mothers assessed as having any degree of depression decreased by 85% from 26/80 (32.5%) to 4/80 (5%).
CONCLUSIONS: The number of nocturnal awakenings requiring parental support among infants aged 6-12 months significantly decreased following a single consultation on infant sleep physiology and teaching behavioural strategies to improve sleep. Significant improvements in maternal stress, anxiety and depression were also observed.
Brian Symon; Michael Bammann; Georgina Crichton; Chris Lowings; James Tucsok
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Publication Detail:
Type:  Journal Article     Date:  2012-09-13
Journal Detail:
Title:  BMJ open     Volume:  2     ISSN:  2044-6055     ISO Abbreviation:  BMJ Open     Publication Date:  2012  
Date Detail:
Created Date:  2012-09-17     Completed Date:  2012-10-02     Revised Date:  2013-03-12    
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Nlm Unique ID:  101552874     Medline TA:  BMJ Open     Country:  England    
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Languages:  eng     Pagination:  -     Citation Subset:  -    
Kensington Park Medical Practice, Adelaide, Australia.
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Journal ID (nlm-ta): BMJ Open
Journal ID (iso-abbrev): BMJ Open
Journal ID (hwp): bmjopen
Journal ID (publisher-id): bmjopen
ISSN: 2044-6055
Publisher: BMJ Group, BMA House, Tavistock Square, London, WC1H 9JR
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© 2012, Published by the BMJ Publishing Group Limited. For permission to use (where not already granted under a licence) please go to
Received Day: 13 Month: 6 Year: 2012
Accepted Day: 15 Month: 8 Year: 2012
collection publication date: Year: 2012
Electronic publication date: Day: 14 Month: 9 Year: 2012
Volume: 2 Issue: 5
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PubMed Id: 22983788
ID: 3467591
Publisher Id: bmjopen-2012-001662
DOI: 10.1136/bmjopen-2012-001662

Reducing postnatal depression, anxiety and stress using an infant sleep intervention Alternate Title:Reducing postnatal depression, anxiety and stress, by improving infant sleep
Brian Symon
Michael Bammann
Georgina Crichton
Chris Lowings
James Tucsok
Kensington Park Medical Practice, Adelaide, Australia
Correspondence to Dr Brian Symon;

Article summary
Article focus
  • Postnatal depression is a common problem with significant morbidity.
  • There is a known correlation with sleep deprivation.
  • By improving infant sleep we have been able to show a reduction in maternal depression, anxiety and stress.
Key messages
  • A behavioural sleep intervention in primary care can improve both infant sleep and maternal mental health.
Strengths and limitations of this study
  • The intervention has been previously demonstrated in an randomised control trial.
  • The study population was self-selected.
  • The subjects were their own controls, before and after design.


Approximately one-third of Australian parents report sleep difficulties in infants between the ages of 1−24 months.1 Between the ages of 6−12 months, this figure has been reported to be as high as 46%.2 Sleep problems in early infancy may have severe adverse consequences, including postnatal depression and maternal anxiety. It is estimated that 10% to 20% of women experience postnatal depression,3 while others experience emotional problems that while less severe than clinical depression may still negatively impact upon maternal well-being.2, 4–6 Maternal depression can have serious and long-term detrimental effects on family well-being and stability, and upon the cognitive and emotional development of the child.7–9 Furthermore, short sleep duration in early infancy can directly affect the child's behavioural competence, cognitive performance and physical development.5 Associations of parental reports of sleep problems with maternal depression have been previously demonstrated.2, 10–12

Patterns that can be characterised as sleep problems include a range of behaviours such as frequent and long nocturnal awakenings, being nursed to sleep, taking prolonged periods to fall asleep, sharing a bed with the parent and only taking short naps during the day. Behavioural interventions involving discussion of infant sleep and guidance on sleep improvement strategies have been previously demonstrated as an effective means of reducing infant sleep problems.13, 14

In a previous randomised controlled trial,14 families were recruited at birth and randomly assigned to the control or intervention group. The intervention was a preventative strategy, a single 45 min consultation from a trained research nurse when the infant was aged between 2 and 3-weeks old. The consultation included a discussion on normal sleep patterns and the use of behavioural techniques to develop ‘independent sleep skill’. Sleep diaries measured sleep performance at 6 and 12 weeks of age. There was significant sleep improvement observed in the intervention group at both follow-up points, including higher mean hours of day, night and total sleep without an increase in infant crying. At 6 weeks of age, infants in the intervention group averaged nearly 9 h more sleep per week and by 12 weeks this had increased to 14.6 h/week. At 12 weeks of age, 62% of the intervention group achieved at least 15 h mean sleep per 24-h period, compared with 36% of controls (p<0.001).

Compared with examining sleep outcomes, fewer studies have examined the effects of such sleep techniques on maternal mental health.15–17 This study applied the same intervention as our original trial14 to self-selected families experiencing sleep problems in infants aged between 6 and 12 months. The primary aims of the study were to examine reported infant nocturnal awakenings and depression, anxiety and stress in mothers after receiving this intervention. A secondary aim was to examine relationships between psychological outcomes and reported nocturnal awakenings. It is hypothesised that following implementation of the behavioural sleep intervention, the number of nocturnal awakenings and maternal depression, anxiety and stress will be significantly reduced.

Study population and setting

Participants were mothers who presented to a metropolitan general medical practice in Adelaide, South Australia, and requesting assistance with infant sleep problems. The practice is a primary care site, which has specialised in the management of sleep problems in children. Patients who presented to the practice between June 2011 and October 2011 and who met the inclusion criteria were invited to participate in a study of maternal health and well-being by the primary researcher. Inclusion criteria were the child's age (6−12 months) and that the visit was the families first to the clinic. There were no other exclusion criteria. All participants gave informed written consent prior to completing the baseline questionnaire and receiving any treatment. Ethics approval was granted from the University of Adelaide Ethics Committee.

Procedure and measures

The Depression Anxiety Stress Scale 21 (DASS21) was completed by participants prior to seeing the clinician at their initial consultation. The DASS21 is a reliable, validated 21-item self-report measure designed to assess anxiety, depression and stress.18–20 Comprising three scales of seven items, each item is scored on a four-point scale ranging from 0, ‘did not apply to me at all’, to 4, ‘applied to me very much, or most of the time’. The Depression scale assesses feelings of hopelessness, pessimism and lack of interest, involvement or enjoyment. The Anxiety scale assesses autonomic arousal, skeletal muscle effects such as shakiness, situational anxiety and performance worry. The Stress scale is sensitive to levels of nervous arousal, tension, ability to relax, irritability and ease of upset or agitation. Scores for Depression, Anxiety and Stress are calculated by summing the scores for each of the relevant items, and multiplying by 2 (to enable comparison with full DASS scores and clinical cut-offs). A severity rating is calculated for each component, ranging from ‘normal’ to ‘extremely severe’. A follow-up DASS21 was completed before seeing the clinician at the second consult 2−3 weeks later, or by phone interview for those who did not return to the clinic. The number of typical nocturnal awakenings (minimum and maximum) was also reported by mothers at baseline and follow-up.


The intervention comprised a 45-consultation provided by an experienced general practitioner (GP) with an expertise in infant sleep (BS) or a registered nurse (CL) trained to provide the same intervention working with the GP's supervision. Both parents were encouraged to attend. This intervention has been previously described,14 but included a discussion on normal sleep patterns in newborn infants (summarised in box 1) and the provision of written material reinforcing this information. The key points emphasised in the information provided were that sleep is cyclical with repeated bouts of waking, and that returning to sleep is driven by both fatigue and appropriate external ‘cues of sleep’ which are learned. Sleep achievement and maintenance are thus regarded as learned skills. Tiredness or more specifically over-tiredness is the enemy of high-quality sleep. Finally, it was emphasised that there is a need to avoid parent-dependent sleep cues as they lead to repeated cycles of ‘requesting’ or ‘signalling’ for parental support within a block of sleep. A ‘cold turkey’ approach was encouraged. A written copy of the tutorial was provided to each parent and they were encouraged to access a website ( where a range of free supporting material was available.

Box 1  Key advice provided to families in consultation intervention

  1. Human sleep is cyclical.
  2. A return to sleep from an awakening is in part driven by external cues of sleep.
  3. Cues of sleep are learned.
  4. Sleep is usefully regarded as a learned skill.
  5. Fatigue interferes with the performance of learned skills. In this context, fatigue impairs performing the skills of achieving and maintaining sleep.
  6. Cues of sleep that are parent independent are the most useful.

Statistical analysis

A sample size of 33 was estimated to give 80% power to detect an effect size of 0.5 between before and after DASS scores, at an α of 0.05. A nominal sample of 100 was chosen to allow for a drop-out rate of up to 50%. Independent sample t tests were used to compare baseline demographic characteristics, and DASS21 scores between those who completed the study, and those who did not complete follow-up. Correlational analyses were used to examine any relationships between psychological outcomes and reported nocturnal awakenings. Paired t tests were used to determine any change in DASS21 scores (depression, anxiety, stress and total) between the two time points for each participant. All statistical analyses were conducted using SPSS for Windows, V.18.0 (SPSS Inc, Chicago, Illinois, USA).


In all, 103 mothers, aged 20−45 years, were invited to participate. Of which 99 were willing to participate, provided written consent and completed a baseline DASS21. Eighty (81%) completed a follow-up DASS21 2–6 weeks later (median time to second measure was 25 days). Fifty-two mothers completed the follow-up DASS21 prior to their second consultation at the practice, and 28 completed the DASS21 by telephone. Of those who withdrew from the study (n=19), two mothers declined to complete the follow-up questionnaire, and 17 were unable to be contacted and did not attend a second visit.

There was no significant difference in mother's age, child's age, depression, anxiety or stress scores or number of nocturnal awakenings at baseline for those who completed the study (n=80), compared to those who withdrew (n=19) (table 1). Families came from a wide variety of socio-economic demographics. The Socio-economic Index for Disadvantage was used to assess socio-economic status, and there was an even spread across all postcodes with no bias towards any advantage or disadvantage.

Nocturnal awakenings

At baseline, 12 (23%) infants had five or more awakenings; 32 (61%) had three or more nocturnal awakenings; 51 (98%) had one or more awakening; and 1 (2%) had no awakenings (table 2). At follow-up these figures had significantly improved, 0 (0%) had five or more nocturnal awakenings; 2 (4%) had three or more nocturnal awakenings; 16 (31%) had one or more awakenings and 36 (69%) had no awakenings.

Maternal stress was significantly and positively correlated with nocturnal awakenings at baseline and follow-up (both p<0.05). Total DASS21 was significantly and positively correlated with nocturnal awakenings at follow-up (p<0.05).

Depression, anxiety and stress

There were significant improvements in Depression, Anxiety and total DASS21 (all p<0.001), and for Stress (p=0.002) between baseline and follow-up (table 2). Improvements were greatest in the following sequence: depression (66% mean score reduction), total DASS21 (49%), anxiety (44%) and stress (42%). Table 3 describes the distribution of DASS21 scores at baseline and follow-up, ranging from normal to extremely severe. Overall, 32.5% of mothers had depression categorised as mild or above at baseline, and at follow-up this figure was 5%. Similarly, 48.8% and 25% of participants had mild or greater stress or anxiety respectively at baseline, which was reduced to 20% for stress and 15% for anxiety post-intervention. There were a total of 27 severe or extremely severe scores in depression, anxiety or stress at baseline. This was reduced to seven scores at follow-up.


It has previously been demonstrated that a single consultation provided in a primary health-care setting can improve infant sleep by up to 14.6 h/week.14 The application of this strategy to families with established sleep problems has demonstrated a clear improvement in infant sleep and importantly, significant improvement in the psychological well-being of mothers. There was a significant reduction in maternal depression, anxiety and stress scores (all p<0.003) following one single sleep behaviour consultation. Importantly, the changes observed reflect a clinically and socially significant improvement in outcome scores. A third of mothers (32.5%) reported at least mild levels of depression at baseline, and at follow-up this figure had decreased to 5%, with similar results for anxiety and stress. Most importantly, the numbers of women in the severe/extremely severe categories at baseline were all reduced at the post-intervention assessment.

Our findings add support to previous studies. Three randomised controlled trials have demonstrated that sleep management programmes can have a beneficial effect on reducing depression prevalence, and improve sleep performance.15–17 Armstrong et al15 implemented an outpatient-based sleep management programme conducted over a longer time frame, and with older children than in the present study. Depression was reduced from 40% of the sample at baseline, to 4.3% at an average of 2 months later. Similarly, this study sample consisted of parents presenting to a sleep clinic and the intervention was the provision of ‘controlled crying’ and ‘cold turkey’ techniques. Significant improvements in sleep parameters also occurred. Controlled crying techniques require the parent to put the baby down awake at sleep times, and allow him to go to sleep with minimal intervention. The infant may cry for a certain time, and if not settled to sleep by this time, parental reassurance is required. This response may involve a check of the infant, a rewrap, or perhaps a short top-up feed, and then returning the infant to attempt to sleep again. This parental response to crying occurs at increasing time intervals.

A larger randomised trial by Hiscock et al16, 17 involved over 300 mothers reporting an infant sleep problem at 7 months of age. The intervention comprised consultations regarding behavioural strategies, the formation of a sleep management plan and handouts on normal sleep patterns. The behavioural intervention consisted of two options: (1) ‘controlled crying’ whereby the parent responded to infant crying at increasing intervals, or (2) ‘camping out’ whereby the parent sat with the infant until they fell asleep, gradually removing their presence over 3 weeks.16, 17 Depression was significantly lower at both 10 and 12 months for the intervention mothers compared with controls, as was the reporting of sleep problems. These improvements appear to have been maintained at 2 years, with intervention mothers having 59% lower odds of reporting depressive symptoms at this time.17

The significant morbidities associated with problems of infant sleep have been reported extensively, particularly postnatal depression. A large meta-analysis of 59 studies, including over 12 000 women and using a range of different assessment methods, estimated that overall prevalence of postpartum depression was 13%.3 Australian studies have reported figures ranging from 6.2%21 to 7.5%,22 with figures increasing to 22.6% when a lower cut-off (for minor depression) is used.23 These studies were all conducted within the first 2 months of the infant's life. Prevalence at longer follow-ups between 5 and 9 months postpartum have shown higher prevalence's of between 13.9% and 16.9% for major depression,24 and 18.2% for minor depression.25 Maternal anxiety, given much less attention than postnatal depression, may also be experienced by a large number of women. Panic attacks or intense anxiety has been reported by up to 15.7% in the first 3 months postpartum, and 8.5% from 6 to 9 months postpartum in Australian mothers.25 Based on the number of registered births in Australia in 2010 (nearly 300 000), and using a prevalence estimate of 15%, a possible 45 000 women per year may experience some degree of postnatal depression, clearly an enormous public health problem. The high rates of maternal anxiety and depression in mothers of infants with sleep problems have been previously demonstrated.2, 10–12 Assisting these mothers to improve their infant's sleep is therefore a very important factor in reducing depression. An effective behavioural strategy, such as the one presented, implemented by parents in the home environment to significantly improve infant sleep could potentially have a significant impact on reducing the rates of postnatal depression in Australian mothers.

It is well established that the detrimental impacts of postpartum depression extend beyond the parent to the child. Deficits in early interactions and cognitive functioning, insecure infant attachment and behavioural disturbances have been associated with postpartum depression.8 Second, the lack of prolonged sleep itself, can have detrimental effects on child development, including behavioural, cognitive and physical parameters.5 An effective intervention, which can improve sleep behaviour in infants, and subsequently symptoms of depression in mothers, may therefore benefit the mother and the child. This is a simple consultation-based strategy, that is, time effective, and can be readily taught to a healthcare professional in a primary care setting. It has the potential to be an extremely cost-effective means of improving infant sleep and maternal mental health.

Some limitations must be acknowledged. Our recruitment methods relied upon women presenting to a local medical practitioner for assistance. These women had therefore identified a problem and been willing to seek help. Women aged under 20, and of non-English-speaking background were likely to have been unrepresented in the study. Data were not collected on other socio-demographic determinants such as family income, education or relationship status. Without this information or comparative population data, the representativeness of the sample cannot be concluded.

The definition of a sleep problem, in the absence of an accepted form of measurement, was defined according to parental report. However, the collection of the number of nocturnal awakenings confirmed that these infants did have broken sleep. We are unable to define the direction of causality between sleep problems and maternal mental health. The intervention employed in the current study, effective in improving infant sleep behaviour, is concurrently targeting psychological well-being.

Information regarding the number of nocturnal awakenings was not obtained from those women who completed the follow-up by telephone (n=28), which is a shortcoming of the study. Measures of maternal sleep quality and quantity, or other measures of maternal health apart from the psychological measures were not obtained. It also must be acknowledged that it is possible that participants were receiving other treatment or assistance for either their depression or their infant's sleep problems during the study period. A major limitation of the before-and-after study design is the inability to control for other external factors that may impact upon the outcomes. Other external factors that may have impacted upon the results, and that were not measured, include family or social stressors. Subsequently, any cause-and-effect conclusions cannot be drawn. Finally, we cannot determine whether non-respondents to the second questionnaire did not have intervention success and therefore were not willing to complete the questionnaire. Despite these limitations, the findings are suggestive that this behavioural technique may be of benefit to mothers experiencing some degree of postnatal depression, anxiety or stress. The intervention may be quite easily replicated by trained physicians or nurses in other primary healthcare settings, particularly in clinical practices that specialise in infant and maternal health.


Our findings indicate that effectively managing infant sleep problems may be a key component of treating postnatal depression. The intervention promotes the development of good sleep habits by putting the infant to sleep awake and without parental intervention. This behavioural intervention may potentially present as a timely and effective technique for reducing postnatal depression, anxiety and stress in mothers. With the adverse impact that both depression and sleep deprivation have on mother and child, the beneficial implications of this intervention for families are immense. Randomised controlled trials are needed to confirm these positive findings, and to examine the impact of the behavioural intervention on infant sleep performance and maternal health, including psychological outcomes and sleep, in the long term.

Supplementary Material Author's manuscript
Reviewer comments


Contributors: BS, JT and MB developed the study design. MB collected patient data. CL and BS delivered the intervention. ML, GC and MB analysed data. GC, BS and MB drafted the manuscript. All authors read and approved the final manuscript.

Competing interests: None.

Provenance and peer review: Not commissioned; externally peer reviewed.

Data sharing statement: Requests for access to data should be made to the corresponding author (

1. Armstrong KL,Quinn RA,Dadds MR. The sleep patterns of normal children. Med J AustYear: 1994;161:202–68035724
2. Hiscock H,Wake M. Infant sleep problems and postnatal depression: a community-based study. PediatricsYear: 2001;107:1317–2211389250
3. Ohara MW,Swain AM. Rates and risk of postpartum depression—a meta-analysis. Int Rev PsychiatryYear: 1996;8:37–54
4. Brown S,Lumley J. Maternal health after childbirth: results of an Australian population based survey. Br J Obstet GynaecolYear: 1998;105:156–619501779
5. Touchette E,Petit D,Tremblay RE,et al. Risk factors and consequences of early childhood dyssomnias: new perspectives. Sleep Med RevYear: 2009;13:355–6119185519
6. Yelland J,Sutherland G,Brown SJ. Postpartum anxiety, depression and social health: findings from a population-based survey of Australian women. BMC Public HealthYear: 2010;10:77121167078
7. Beck CT. The effects of postpartum depression on child development: a meta-analysis. Arch Psychiatr NursYear: 1998;12:12–209489170
8. Murray L,Cooper PJ. The impact of postpartum depression on child development. Int Rev PsychiatryYear: 1996;8:55–63
9. Cogill SR,Caplan HL,Alexandra H,et al. Impact of maternal postnatal depression on cognitive development of young children. BMJYear: 1986;292:1165–73085767
10. Lam P,Hiscock H,Wake M. Outcomes of infant sleep problems: a longitudinal study of sleep, behavior, and maternal well-being. PediatricsYear: 2003;111:e203–712612272
11. Zuckerman B,Stevenson J,Bailey V. Sleep problems in early childhood—continuities, predictive factors, and behavioral correlates. PediatricsYear: 1987;80:664–713670967
12. Armstrong KL,O'Donnell H,McCallum R,et al. Childhood sleep problems: association with prenatal factors and maternal distress/depression. J Paediatr Child HealthYear: 1998;34:263–69633975
13. Hiscock H,Wake M. Randomised controlled trial of behavioural infant sleep intervention to improve infant sleep and maternal mood. BMJYear: 2002;324:1062–511991909
14. Symon BG,Marley JE,Martin AJ,et al. Effect of a consultation teaching behaviour modification on sleep performance in infants: a randomised controlled trial. Med J AustYear: 2005;182:215–1815748130
15. Armstrong KL,Van Haeringen AR,Dadds MR,et al. Sleep deprivation or postnatal depression in later infancy: separating the chicken from the egg. J Paediatr Child HealthYear: 1998;34:260–29633974
16. Hiscock H,Bayer J,Gold L,et al. Improving infant sleep and maternal mental health: a cluster randomised trial. Arch Dis ChildYear: 2007;92:952–817158146
17. Hiscock H,Bayer JK,Hampton A,et al. Long-term mother and child mental health effects of a population-based infant sleep intervention: cluster-randomized, controlled trial. PediatricsYear: 2008; 122:E621–718762495
18. Crawford JR,Henry JD. The Depression Anxiety Stress Scales (DASS): normative data and latent structure in a large non-clinical sample. Br J Clin PsycholYear: 2003;42:111–3112828802
19. Lovibond PF,Lovibond SH. The structure of negative emotional states: comparison of the Depression Anxiety Stress Scales (DASS) with the Beck depression and anxiety inventories. Behav Res TherYear: 1995;33:335–437726811
20. Lovibond SH,Lovibond PF. Manual for the depression anxiety stress scales. 2nd ednSydney: Psychology Foundation, Year: 1995
21. Eastwood JG,Phung H,Barnett B. Postnatal depression and socio-demographic risk: factors associated with Edinburgh Depression Scale scores in a metropolitan area of New South Wales, Australia. Aust N Z J PsychiatryYear: 2011;45:1040–622017687
22. Buist AE,Austin MPV,Hayes BA,et al. Postnatal mental health of women giving birth in Australia 2002–2004: findings from the beyondblue National Postnatal Depression Program. Aust N Z J PsychiatryYear: 2008;42:66–7318058446
23. Edwards B,Galletly C,Semmler-Booth T,et al. Does antenatal screening for psychosocial risk factors predict postnatal depression? A follow-up study of 154 women in Adelaide, South Australia. Aust N Z J PsychiatryYear: 2008;42:51–518058444
24. Brown S,Bruinsma F,Darcy MA,et al. Early discharge: no evidence of adverse outcomes in three consecutive population-based Australian surveys of recent mothers, conducted in 1989, 1994 and 2000. Paediatr Perinat EpidemiolYear: 2004;18:202–1315130160
25. Woolhouse H,Brown S,Krastev A,et al. Seeking help for anxiety and depression after childbirth: results of the Maternal Health Study. Arch Women Ment HealthYear: 2009;12:75–83

[TableWrap ID: BMJOPEN2012001662TB1] Table 1 

Comparison of those who completed the study and those who withdrew at baseline

Mean (SD)
Completed (n=80) Withdrawals (n=19) Total (n=99)
Maternal age at baseline (years) 32.5 (5.0) 32.0 (4.7) 32.4 (4.9)
Child's age at baseline (months) 8.5 (1.7) 8.4 (2.3) 8.4 (1.8)
Minimum number of nocturnal awakenings 3.0 (2.0) 3.8 (2.2) 3.2 (2.1)
Maximum number of nocturnal awakenings 4.4 (3.3) 5.4 (4.1) 4.6 (3.4)
Baseline depression 7.9 (8.3) 6.2 (4.2) 7.6 (7.7)
Baseline anxiety 4.6 (6.3) 4.2 (6.0) 4.5 (6.2)
Baseline stress 16.6 (9.4) 16.8 (11.4) 16.6 (9.8)
Baseline DASS21 total 29.1 (21.1) 27.3 (20.0) 28.7 (20.8)

DASS, Depression, Anxiety, Stress Scale.

[TableWrap ID: BMJOPEN2012001662TB2] Table 2 

Baseline, follow-up and change in DASS21 scores and number of nocturnal awakenings

Baseline Follow-up

n Mean (SD)
Mean change (95% CI) Percentage change p Value*
Primary outcomes
 Depression 80 7.9 (8.3) 2.8 (4.7) 5.2 (3.7 to 6.7) 65.8 <0.0001
 Anxiety 80 4.6 (6.3) 2.6 (4.6) 2.0 (0.7 to 3.2) 43.5 0.002
 Stress 80 16.6 (9.4) 9.5 (7.8) 7.0 (5.1 to 9.0) 42.2 <0.0001
 DASS21 total 80 29.1 (21.1) 14.9 (15.8) 14.2 (10.2 to 18.2) 48.8 <0.0001
Secondary outcomes
 Minimum number awakenings 52 3.3 (2.2) 0.4 (0.8) 2.9 (2.2 to 3.5) 87.8 <0.0001
 Maximum number awakenings 52 4.9 (3.6) 0.5 (0.8) 4.4 (3.4 to 5.5) 89.8 <0.0001

*Probability of differences between the two time points (paired sample t tests).

DASS, Depression, Anxiety, Stress Scale.

[TableWrap ID: BMJOPEN2012001662TB3] Table 3 

Distribution of depression, anxiety and depression scores at baseline and follow-up, ranging from normal to extremely severe for n=80

Baseline Follow-up

n (%)
 Depression 0–9 54 (67.5) 76 (95)
 Anxiety 0–7 60 (75.0) 68 (85)
 Stress 0–14 41 (51.2) 64 (80)
 Depression 10–13 13 (16.3) 0
 Anxiety 8–9 6 (7.5) 5 (6.3)
 Stress 15–18 12 (15.0) 10 (12.5)
 Depression 14–20 6 (7.5) 3 (3.8)
 Anxiety 10–14 9 (11.3) 5 (6.3)
 Stress 19–25 12 (15.0) 2 (2.5)
 Depression 21–27 3 (3.8) 0
 Anxiety 15–19 1 (1.3) 0
 Stress 26–33 10 (12.5) 2 (2.5)
Extremely severe
 Depression 28+ 4 (5.0) 1 (1.3)
 Anxiety 20+ 4 (5.0) 2 (2.5)
 Stress 34+ 5 (6.3) 2 (2.5)

Article Categories:
  • General practice / Family practice
    • Research
Article Categories:
  • 1506
  • 1696
  • 1719
  • 1712

Keywords: Mental Health, Sleep Medicine.

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