| Reducing noninfectious risks of blood transfusion. | |
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MedLine Citation:
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PMID: 21792054 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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As screening for transfusion-associated infections has improved, noninfectious complications of transfusion now cause the majority of morbidity and mortality associated with transfusion in the United States. For example, transfusion-related acute lung injury, transfusion-associated circulatory overload, and hemolytic transfusion-reactions are the first, second, and third leading causes of death from transfusion, respectively. These complications and others are reviewed, and several controversial methods for prevention of noninfectious complications of transfusion are discussed, including universal leukoreduction of erythrocyte units, use of male-only plasma, and restriction of erythrocyte storage age. |
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Authors:
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Brian M Gilliss; Mark R Looney; Michael A Gropper |
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Publication Detail:
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Type: Journal Article; Research Support, N.I.H., Extramural; Review |
Journal Detail:
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Title: Anesthesiology Volume: 115 ISSN: 1528-1175 ISO Abbreviation: Anesthesiology Publication Date: 2011 Sep |
Date Detail:
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Created Date: 2011-08-25 Completed Date: 2011-10-24 Revised Date: 2012-02-14 |
Medline Journal Info:
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Nlm Unique ID: 1300217 Medline TA: Anesthesiology Country: United States |
Other Details:
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Languages: eng Pagination: 635-49 Citation Subset: AIM; IM |
Affiliation:
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Department of Anesthesia and Perioperative Care, University of California, San Francisco, California 94143-0624, USA. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Acute Lung Injury
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etiology Adult Blood Preservation Blood Transfusion / adverse effects* Chimerism Evidence-Based Practice Fever / etiology Graft vs Host Disease Hemolysis Humans Hypersensitivity / etiology Hypotension / etiology Immunomodulation Leukocyte Reduction Procedures Plasma Purpura / etiology Risk Reduction Behavior |
| Grant Support | |
ID/Acronym/Agency:
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5P50HL08102/HL/NHLBI NIH HHS; R01 HL107386/HL/NHLBI NIH HHS; R01 HL107386-02/HL/NHLBI NIH HHS |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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