Document Detail


Reduced stereoacuity in Williams syndrome.
MedLine Citation:
PMID:  8985489     Owner:  NLM     Status:  MEDLINE    
Abstract/OtherAbstract:
Strabismus is a frequently recognized manifestation of Williams syndrome [Greenberg and Lewis, 1988: Ophthalmology 95:1608-1612; Kapp et al., 1995: Am J Ophthalmol 119:355-360]. We recently evaluated the ophthalmologic function of 12 patients with Williams syndrome (WS), with an emphasis on binocularity. Four of 12 patients (33%) had measurable strabismus. Of the 8 remaining patients, examination of binocular function was possible in 6, all of whom demonstrated reduced stereoacuity. We speculate that subnormal binocular vision and the poor visuospatial performance observed in patients with WS may be related to abnormal brain morphogenesis in the region of the occipitoparietal cortex.
Authors:
L S Sadler; S E Olitsky; J D Reynolds
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  American journal of medical genetics     Volume:  66     ISSN:  0148-7299     ISO Abbreviation:  Am. J. Med. Genet.     Publication Date:  1996 Dec 
Date Detail:
Created Date:  1997-03-21     Completed Date:  1997-03-21     Revised Date:  2004-11-17    
Medline Journal Info:
Nlm Unique ID:  7708900     Medline TA:  Am J Med Genet     Country:  UNITED STATES    
Other Details:
Languages:  eng     Pagination:  287-8     Citation Subset:  IM    
Affiliation:
Department of Pediatrics, State University of New York at Buffalo, Children's Hospital, NY 14222, USA.
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MeSH Terms
Descriptor/Qualifier:
Adolescent
Adult
Child
Child, Preschool
Esotropia / physiopathology
Humans
Infant
Male
Vision Disorders / physiopathology*
Vision, Binocular
Visual Acuity*
Williams Syndrome / physiopathology*

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine


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