| Reduced selection for codon usage bias in Drosophila miranda. | |
| | |
MedLine Citation:
|
PMID: 17457633 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Biased codon usage in many species results from a balance among mutation, weak selection, and genetic drift. Here I show that selection to maintain biased codon usage is reduced in Drosophila miranda relative to its ancestor. Analyses of mutation patterns in noncoding DNA suggest that the extent of this reduction cannot be explained by changes in mutation bias or by biased gene conversion. Low levels of variability in D. miranda relative to its sibling species, D. pseudoobscura, suggest that it has a much smaller effective population size. Reduced codon usage bias in D. miranda may thus result from the reduced efficacy of selection against newly arising mutations to unpreferred codons. |
| | |
Authors:
|
Doris Bachtrog |
Related Documents
:
|
7042453 - Periodic selection, infectious gene exchange and the genetic structure of e. coli popul... 15122503 - Selection in modular organisms: is intraclonal variation in macroalgae evolutionarily i... 18082573 - Hla class i polymorphism in the cuban population. |
Publication Detail:
|
Type: Journal Article; Research Support, N.I.H., Extramural Date: 2007-04-24 |
Journal Detail:
|
Title: Journal of molecular evolution Volume: 64 ISSN: 0022-2844 ISO Abbreviation: J. Mol. Evol. Publication Date: 2007 May |
Date Detail:
|
Created Date: 2007-05-07 Completed Date: 2007-08-30 Revised Date: 2009-11-19 |
Medline Journal Info:
|
Nlm Unique ID: 0360051 Medline TA: J Mol Evol Country: Germany |
Other Details:
|
Languages: eng Pagination: 586-90 Citation Subset: IM |
Affiliation:
|
Division of Biological Sciences, University of California, San Diego, 9500 Gilman Drive, MC 0116, La Jolla, CA 92093, USA. dbachtrog@ucsd.edu |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Animals Codon / genetics* Drosophila / classification, genetics* Evolution, Molecular* Genetic Variation Selection, Genetic* |
| Grant Support | |
ID/Acronym/Agency:
|
GM076007/GM/NIGMS NIH HHS |
| Chemical | |
Reg. No./Substance:
|
0/Codon |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Time- and dose-related effects of three 5-HT receptor ligands on the genioglossus activity in anesth...
Next Document: Unique regulation of the Calvin cycle in the ultrasmall green alga Ostreococcus.