Document Detail

Reduced risk of atopic sensitization among farmers: the Humboldt study.
MedLine Citation:
PMID:  17664888     Owner:  NLM     Status:  MEDLINE    
BACKGROUND: It needs to be clarified whether farming is associated with a reduced risk of atopy or allergic condition. There is a lack of consistent evidence for prevalences of atopy, respiratory allergy and asthma in adult farmers. METHODS: A cross-sectional study of adults (n = 2,081) was conducted in the town of Humboldt, Sask. Allergy skin prick tests were conducted to determine atopic sensitization. Respiratory allergy and physician-diagnosed asthma were based on self-reporting. Logistic regression was used to assess the associations of atopy, respiratory allergy and asthma with farming practices, adjusting for other important variables. RESULTS: Of 2,081 participants, 27.8% were farmers. Reduced risks of atopic sensitization, respiratory allergy and asthma were observed among farmers compared to non-farmers. After adjustment for sex and age, which are major confounders, the odds ratio for atopic sensitization was 0.79 (95% confidence interval: 0.65, 0.97) for farmers versus non-farmers. Asthma showed a similar trend; however, there was no statistically significant difference in either respiratory allergy or asthma rates observed between farmers and non-farmers. CONCLUSIONS: The prevalence of atopy was lower in adult farmers than in non-farmers.
Yue Chen; Donna Rennie; Yvon Cormier; Helen McDuffie; Punam Pahwa; James Dosman
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Publication Detail:
Type:  Journal Article; Research Support, Non-U.S. Gov't     Date:  2007-07-11
Journal Detail:
Title:  International archives of allergy and immunology     Volume:  144     ISSN:  1423-0097     ISO Abbreviation:  Int. Arch. Allergy Immunol.     Publication Date:  2007  
Date Detail:
Created Date:  2007-11-16     Completed Date:  2007-12-18     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  9211652     Medline TA:  Int Arch Allergy Immunol     Country:  Switzerland    
Other Details:
Languages:  eng     Pagination:  338-42     Citation Subset:  IM    
Copyright Information:
Copyright 2007 S. Karger AG, Basel.
Department of Epidemiology and Community Medicine, Faculty of Medicine, University of Ottawa, Ottawa, Ont., Canada.
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MeSH Terms
Allergens / adverse effects,  immunology
Asthma / epidemiology*
Canada / epidemiology
Cross-Sectional Studies
Hypersensitivity, Immediate / epidemiology*
Respiratory Hypersensitivity / epidemiology*
Skin Tests
Reg. No./Substance:

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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