| Reduced platelet sialyltransferase activity in patients with primary release disorder. | |
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MedLine Citation:
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PMID: 6106096 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Platelet sialyltransferase activity was determined in four patients with primary platelet release disorder. Basal enzyme activity was significantly reduced in all. Moreover, enzyme activity in response to stimulation by collagen or sodium arachidonate was also reduced. Platelet total and surface sialic-acid content was normal. The results indicate that defective membrane sialytransferase may be involved in the pathogenesis of primary platelet release disorder. |
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Authors:
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K K Wu; C S Ku; Y C Chen |
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Publication Detail:
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Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Lancet Volume: 2 ISSN: 0140-6736 ISO Abbreviation: Lancet Publication Date: 1980 Aug |
Date Detail:
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Created Date: 1980-11-24 Completed Date: 1980-11-24 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 2985213R Medline TA: Lancet Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 441-3 Citation Subset: AIM; IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Adenine Nucleotides
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blood Adenosine Diphosphate / secretion Adult Aged Blood Platelet Disorders / enzymology*, physiopathology Blood Platelets / enzymology* Female Hemorrhage / enzymology, genetics Humans Platelet Function Tests Sialyltransferases / blood* Transferases / blood* |
| Chemical | |
Reg. No./Substance:
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0/Adenine Nucleotides; 58-64-0/Adenosine Diphosphate; EC 2.-/Transferases; EC 2.4.99.-/Sialyltransferases |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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