| Reduced left ventricular relaxation velocity after acute myocardial infarction. | |
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MedLine Citation:
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PMID: 9649907 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Diastolic left ventricular function is usually described using Doppler recording of the early to atrial (E/A) ratio. However, because of pseudonormalization in patients with moderately impaired diastolic function, the E/A ratio does not allow a meaningful comparison between a group of patients with varying degrees of dysfunction, e.g. after acute myocardial infarction (AMI), and a group of healthy control subjects. In this study, diastolic function was assessed using the E/A ratio, deceleration time of early mitral inflow and maximal longitudinal relaxation velocity. The relaxation velocity was measured using echocardiographic M-mode recording of mitral annulus motion. Mitral annulus motion was recorded in four- and two-chamber views. Relaxation velocities were measured in the septal, lateral, anterior and posterior parts of the mitral annulus and the mean value (RVm) was calculated. Twenty-two consecutive patients were investigated 3-21 days after first transmural AMI. Twenty-two healthy subjects of similar age served as a control group. The group of patients with AMI had an RVm of 40.9 +/- 15.4 mm s-1 compared with 68.5 +/- 12.4 mm s-1 in the control group (P < 0.0001). In contrast, the E/A ratio, deceleration time and heart rate did not differ significantly between the two groups. The results suggest that maximal longitudinal relaxation velocity is a simple and appropriate measure of diastolic function in patients with transmural AMI. |
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Authors:
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L Bojö; B Wandt; N G Ahlin |
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Publication Detail:
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Type: Clinical Trial; Comparative Study; Controlled Clinical Trial; Journal Article |
Journal Detail:
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Title: Clinical physiology (Oxford, England) Volume: 18 ISSN: 0144-5979 ISO Abbreviation: Clin Physiol Publication Date: 1998 May |
Date Detail:
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Created Date: 1998-09-18 Completed Date: 1998-09-18 Revised Date: 2007-11-15 |
Medline Journal Info:
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Nlm Unique ID: 8309768 Medline TA: Clin Physiol Country: ENGLAND |
Other Details:
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Languages: eng Pagination: 195-201 Citation Subset: IM |
Affiliation:
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Department of Clinical Physiology Central Hospital, Karlstad, Sweden. |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Aged Blood Flow Velocity Blood Pressure / physiology Diastole / physiology Echocardiography Echocardiography, Doppler Female Hemodynamics / physiology Humans Male Middle Aged Mitral Valve / physiopathology, ultrasonography* Myocardial Infarction / physiopathology, ultrasonography* Observer Variation Reproducibility of Results Ultrasonography, Doppler, Pulsed Ventricular Dysfunction, Left / physiopathology, ultrasonography* |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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