| Reduced high density lipoproteins as a risk factor after acute myocardial infarction. | |
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MedLine Citation:
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PMID: 3111177 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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In a group of normocholesterolemic, non-diabetic middle-aged males surviving an acute myocardial infarction for 4 +/- 2 years (mean +/- SD), we have previously described a low apolipoprotein A-I and a deficient fibrinolytic activity as two major characteristics. In the present study we have followed morbidity and mortality risk factors for five years in these males. Mortality was 40% in a hypertensive group and 16% in a normotensive group. In the normotensive group mortality was related to reinfarction. Furthermore, patients with a poor prognosis in the normotensive group had lower high density lipoprotein (HDL) cholesterol and lower apolipoprotein A-I concentration in plasma than patients with a good prognosis. Unexpectedly, in the hypertensive group death was related to a low (p less than 0.05) cortisol concentration in urine. It is concluded that a low HDL level may be a bad prognostic sign in males who have sustained an acute myocardial infarction and show no evidence of other risk factors, such as diabetes, hypercholesterolemia or hypertension. |
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Authors:
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J Franzén; B W Johansson; A Gustafson |
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Publication Detail:
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Type: Journal Article; Research Support, Non-U.S. Gov't |
Journal Detail:
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Title: Acta medica Scandinavica Volume: 221 ISSN: 0001-6101 ISO Abbreviation: Acta Med Scand Publication Date: 1987 |
Date Detail:
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Created Date: 1987-08-05 Completed Date: 1987-08-05 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 0370330 Medline TA: Acta Med Scand Country: SWEDEN |
Other Details:
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Languages: eng Pagination: 357-62 Citation Subset: IM |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Apolipoprotein A-I Apolipoproteins A / blood* Cholesterol, HDL / blood* Humans Lipoproteins, HDL / blood* Male Middle Aged Myocardial Infarction / blood*, mortality Recurrence Risk Triglycerides / blood |
| Chemical | |
Reg. No./Substance:
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0/Apolipoprotein A-I; 0/Apolipoproteins A; 0/Cholesterol, HDL; 0/Lipoproteins, HDL; 0/Triglycerides |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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