Document Detail

Reduced heart rate recovery is associated with poorer cognitive function in older adults with cardiovascular disease.
MedLine Citation:
PMID:  22988485     Owner:  NLM     Status:  PubMed-not-MEDLINE    
Cardiovascular disease (CVD) in older adults has been associated with varying degrees of cognitive dysfunction. Several mechanisms may explain this association, including impaired cardiovascular reactivity to autonomic nervous system (ANS) signaling. Reduced heart rate recovery following a stress test may be considered an indication of impaired ANS function (i.e., reduced parasympathetic activity). Participants were 47 older adults (53-83 years) who underwent a treadmill stress test and were administered a comprehensive neuropsychological battery upon entry to phase II cardiac rehabilitation. Reduced parasympathetic activity was associated with impaired cognitive performance on a measure of global cognitive function and on tasks of speeded executive function and confrontation naming. These relationships suggest that changes in autonomic function may be mechanistically related to the impaired cognitive function prevalent in CVD patients.
Therese A Keary; Rachel Galioto; Joel Hughes; Donna Waechter; Mary Beth Spitznagel; James Rosneck; Richard Josephson; John Gunstad
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Publication Detail:
Type:  Journal Article     Date:  2012-09-04
Journal Detail:
Title:  Cardiovascular psychiatry and neurology     Volume:  2012     ISSN:  2090-0171     ISO Abbreviation:  Cardiovasc Psychiatry Neurol     Publication Date:  2012  
Date Detail:
Created Date:  2012-09-18     Completed Date:  2012-09-19     Revised Date:  2013-04-02    
Medline Journal Info:
Nlm Unique ID:  101516142     Medline TA:  Cardiovasc Psychiatry Neurol     Country:  Egypt    
Other Details:
Languages:  eng     Pagination:  392490     Citation Subset:  -    
Department of Psychology, Kent State University, Kent, OH 44242, USA.
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