Document Detail

Reduced blood pressure variability in ASCOT-BPLA trial favours use of amlodipine/perindopril combination to reduce stroke risk.
MedLine Citation:
PMID:  20532438     Owner:  NLM     Status:  MEDLINE    
Lower within-individual visit-to-visit variability in blood pressure readings in the amlodipine/perindopril combination treatment arm of the ASCOT study has been shown to account for the more effective stroke reduction rate with this combination compared to atenolol and diuretic-based therapies, despite overall similar blood pressure lowering.
J Aalbers
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Publication Detail:
Type:  Journal Article    
Journal Detail:
Title:  Cardiovascular journal of Africa     Volume:  21     ISSN:  1995-1892     ISO Abbreviation:  Cardiovasc J Afr     Publication Date:    2010 Mar-Apr
Date Detail:
Created Date:  2010-06-09     Completed Date:  2010-07-29     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101313864     Medline TA:  Cardiovasc J Afr     Country:  South Africa    
Other Details:
Languages:  eng     Pagination:  115     Citation Subset:  IM    
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MeSH Terms
Amlodipine / therapeutic use*
Angiotensin-Converting Enzyme Inhibitors / therapeutic use
Blood Pressure / drug effects*
Calcium Channel Blockers / therapeutic use
Congresses as Topic
Drug Therapy, Combination
Hypertension / complications,  drug therapy*,  physiopathology
Perindopril / therapeutic use*
Randomized Controlled Trials as Topic
Stroke / etiology,  prevention & control*
Treatment Outcome
Reg. No./Substance:
0/Angiotensin-Converting Enzyme Inhibitors; 0/Calcium Channel Blockers; 82834-16-0/Perindopril; 88150-42-9/Amlodipine

From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine

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