| Reduced aortic elastic properties in a child with Takayasu arteritis: case report and literature review. | |
| | |
MedLine Citation:
|
PMID: 16044277 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
|
Takayasu arteritis (TA) is a chronic inflammatory vasculitis of the aorta and its major branches with a very low incidence in Europe and North America. Our objective was to determine the elastic properties of the affected ascending and descending aortic walls non-invasively in a 14-year-old Iraqi girl with a 3-year history of fever, fatigue, malaise and diffuse pain. Ultrasound and magnetic resonance angiography showed marked thickening of the aortic wall, dilatation of the aortic arch, and decreased luminal diameters of the abdominal aorta and both subclavian arteries, consistent with TA. Ascending and descending aortic elastic properties such as distensibility and stiffness index were markedly reduced compared to a group of healthy controls (n=39): ascending aortic distensibility was 20 kPa(-1) x 10(-3) versus 63+/-23 kPa(-1) x 10(-3) in controls, and the ascending aortic stiffness index 9.6 versus 3.5+/-1.3 in controls. Although the patient's general condition improved rapidly on oral prednisolone and azathioprine and inflammatory parameters normalised within 3 weeks, the aortic elastic parameters did not change during the first 2 weeks of anti-inflammatory treatment. Unfortunately, no further follow-up was possible. CONCLUSION: In patients with Takayasu arteritis, non-invasive quantification of reduced aortic elastic properties can help to assess aortic involvement, and possibly to follow disease activity and vascular response to therapy. |
| | |
Authors:
|
Daniela Baumgartner; Michaela Sailer-Höck; Christian Baumgartner; Thomas Trieb; Heiner Maurer; Michael Schirmer; Lothar-Bernd Zimmerhackl; Jörg-Ingolf Stein |
Related Documents
:
|
10773797 - Takayasu disease with predominant pulmonary involvement. 12692357 - Bilateral scalp necrosis with giant cell arteritis. 17203007 - Technology insight: the role of color and power doppler ultrasonography in rheumatology. 17932577 - Massive progression of annuloaortic ectasia in a patient with takayasu aortitis. 7972817 - Multiple intrahepatic aneurysms following transcatheter arterial embolization. work in ... 11716637 - The influence of hand hygiene prior to insertion of peripheral venous catheters on the ... |
Publication Detail:
|
Type: Case Reports; Journal Article; Review Date: 2005-07-26 |
Journal Detail:
|
Title: European journal of pediatrics Volume: 164 ISSN: 0340-6199 ISO Abbreviation: Eur. J. Pediatr. Publication Date: 2005 Nov |
Date Detail:
|
Created Date: 2005-10-19 Completed Date: 2006-07-10 Revised Date: 2007-11-15 |
Medline Journal Info:
|
Nlm Unique ID: 7603873 Medline TA: Eur J Pediatr Country: Germany |
Other Details:
|
Languages: eng Pagination: 685-90 Citation Subset: IM |
Affiliation:
|
Division of Paediatric Cardiology, Department of Paediatrics, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria. daniela.baumgartner@aon.at |
Export Citation:
|
APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
|
Abdominal Pain
/
etiology Adolescent Aorta / drug effects, pathology*, physiopathology Azathioprine / therapeutic use Female Fever / etiology Glucocorticoids / therapeutic use Humans Immunosuppressive Agents / therapeutic use Magnetic Resonance Angiography Magnetic Resonance Imaging Prednisolone / therapeutic use Takayasu Arteritis / complications, diagnosis*, drug therapy Treatment Outcome Ventricular Function, Left / drug effects |
| Chemical | |
Reg. No./Substance:
|
0/Glucocorticoids; 0/Immunosuppressive Agents; 446-86-6/Azathioprine; 50-24-8/Prednisolone |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
Previous Document: Long-term serial echocardiographic examination of late anthracycline cardiotoxicity and its preventi...
Next Document: Nineteen cases of persistent pruritic nodules and contact allergy to aluminium after injection of co...