Document Detail


Reduced UV light scattering in PDMS microfluidic devices.
MedLine Citation:
PMID:  21218249     Owner:  NLM     Status:  Publisher    
Abstract/OtherAbstract:
Microfluidic devices which consist of polydimethylsiloxane (PDMS) are used extensively for the production of polymer microparticles through the use of droplet templating and on-chip photopolymerization. However, in existing methods, spatial confinement of the photochemical droplet solidification is impaired by UV light scattering inside the PDMS elastomer. We present a technique to load PDMS microfluidic devices with a fluorescent dye that absorbs the scattered UV light and shifts it to longer wavelengths. By this means, the stray light is no longer harmful, and UV exposure can be limited to a desired region on the microfluidic chip.
Authors:
Sebastian Seiffert; Janine Dubbert; Walter Richtering; David A Weitz
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Publication Detail:
Type:  JOURNAL ARTICLE     Date:  2011-1-10
Journal Detail:
Title:  Lab on a chip     Volume:  -     ISSN:  1473-0197     ISO Abbreviation:  -     Publication Date:  2011 Jan 
Date Detail:
Created Date:  2011-1-10     Completed Date:  -     Revised Date:  -    
Medline Journal Info:
Nlm Unique ID:  101128948     Medline TA:  Lab Chip     Country:  -    
Other Details:
Languages:  ENG     Pagination:  -     Citation Subset:  -    
Affiliation:
Harvard University, School of Engineering and Applied Sciences, 29 Oxford Street, Cambridge, Massachusetts 02138, USA. seiffert@seas.harvard.edu.
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