| Redox status of dogs with non-hodgkin lymphomas. An ESR study. | |
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MedLine Citation:
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PMID: 15914284 Owner: NLM Status: MEDLINE |
Abstract/OtherAbstract:
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Free radical and antioxidant parameters in healthy dogs (n=10) and dogs with non-Hodgkin lymphomas (n=11) were measured in blood and lymph node tissue samples before chemotherapy. Enzymatic and other biochemical measurements were performed. We found that (i) free radical concentrations based on ESR spectra of tissues correlated with higher proliferative character; (ii) lymphoma cases showed an impaired antioxidant status; (iii) tumors with low oxidative burst capacity and higher reduced/oxidized glutathione ratio responded better to chemotherapy; and (iv) affected blood and lymph nodes were under strong oxidative stress. |
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Authors:
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Péter Vajdovich; Tamás Kriska; Miklós Mézes; Piroska Ribiczey Szabó; Nándor Balogh; András Bánfi; Attila Arany-Tóth; Tibor Gaál; Judit Jakus |
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Publication Detail:
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Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't Date: 2004-12-25 |
Journal Detail:
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Title: Cancer letters Volume: 224 ISSN: 0304-3835 ISO Abbreviation: Cancer Lett. Publication Date: 2005 Jun |
Date Detail:
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Created Date: 2005-05-25 Completed Date: 2005-07-19 Revised Date: 2006-11-15 |
Medline Journal Info:
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Nlm Unique ID: 7600053 Medline TA: Cancer Lett Country: Ireland |
Other Details:
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Languages: eng Pagination: 339-46 Citation Subset: IM |
Affiliation:
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Department of Internal Medicine and Clinics, Faculty of Veterinary Sciences, Szent István University, Budapest, Hungary. pvajdo@univet.hu |
Export Citation:
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APA/MLA Format Download EndNote Download BibTex |
| MeSH Terms | |
Descriptor/Qualifier:
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Animals Antioxidants / analysis* Cell Proliferation Dog Diseases / physiopathology* Dogs Female Free Radicals / blood* Lymphoma, Non-Hodgkin / physiopathology*, veterinary* Male Oxidative Stress Spectrum Analysis |
| Chemical | |
Reg. No./Substance:
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0/Antioxidants; 0/Free Radicals |
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine
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