Document Detail

Redefinition of the Q wave -- is there a clinical problem?
MedLine Citation:
PMID:  16563898     Owner:  NLM     Status:  MEDLINE    
This study evaluated the potential consequences of the redefined joint European/American electrocardiographic criteria for an established myocardial infarction (MI). New and previous diagnostic Q-wave criteria were used in patients with stable angina pectoris. Seventy-nine patients with and 77 patients without a documented previous MI were compared using the results of myocardial perfusion imaging at rest as a reference. With the new Q-wave criteria, 71% of the former group and 40% of the latter had evidence of established MI compared with 33% and 3% when using the previous criteria (p <0.0001). Sensitivity, specificity, and positive and negative predictive values were 71%, 60%, 64%, and 67% for the new criteria versus 33%, 97%, 93%, and 59% with the previous criteria. These data suggest that that the new Q-wave criteria may be too nonspecific, resulting in an inappropriately high number of false-positive results.
Jesper K Jensen; Kristian Øvrehus; Mette Møldrup; Hans Mickley; Poul Flemming Høilund-Carlsen
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Publication Detail:
Type:  Journal Article     Date:  2006-02-13
Journal Detail:
Title:  The American journal of cardiology     Volume:  97     ISSN:  0002-9149     ISO Abbreviation:  Am. J. Cardiol.     Publication Date:  2006 Apr 
Date Detail:
Created Date:  2006-03-27     Completed Date:  2006-05-04     Revised Date:  2007-11-15    
Medline Journal Info:
Nlm Unique ID:  0207277     Medline TA:  Am J Cardiol     Country:  United States    
Other Details:
Languages:  eng     Pagination:  974-6     Citation Subset:  AIM; IM    
Department of Cardiology, Odense University Hospital, Odense, Denmark.
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MeSH Terms
Case-Control Studies
False Negative Reactions
False Positive Reactions
Middle Aged
Myocardial Infarction / diagnosis*,  physiopathology*,  radionuclide imaging
Practice Guidelines as Topic
Reproducibility of Results
Sensitivity and Specificity

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